STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GLB1L3Beta-galactosidase-1-like protein 3; Galactosidase beta 1 like 3. (653 aa)    
Predicted Functional Partners:
PATE3
Prostate and testis expressed 3; Belongs to the PATE family.
      
 0.626
PATE2
Prostate and testis expressed 2.
   
  
 0.590
SIL1
Nucleotide exchange factor SIL1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone HSPA5; Belongs to the SIL1 family.
    
 
 0.583
PATE1
Prostate and testis expressed 1; Belongs to the PATE family.
   
  
 0.580
MON1B
MON1 homolog B, secretory trafficking associated; Belongs to the MON1/SAND family.
      
 0.517
CLPSL2
Colipase-like protein 2; Colipase like 2.
      
 0.507
SPINK14
Serine protease inhibitor Kazal-type 14; May be a serine protease inhibitor.
      
 0.481
CPVL
Probable serine carboxypeptidase CPVL; May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation; Belongs to the peptidase S10 family.
   
 
 0.472
ZYG11B
Protein zyg-11 homolog B; Serves as substrate adapter subunit in the E3 ubiquitin ligase complex ZYG11B-CUL2-Elongin BC. Acts redudantly with ZER1 to target substrates bearing N-terminal glycine degrons for proteasomal degradation. Involved in the clearance of proteolytic fragments generated by caspase cleavage during apoptosis since N-terminal glycine degrons are strongly enriched at caspase cleavage sites. Also important in the quality control of protein N-myristoylation in which N-terminal glycine degrons are conditionally exposed after a failure of N- myristoylation.
    
 
 0.446
RNASE13
Probable inactive ribonuclease-like protein 13; Does not exhibit any ribonuclease activity; Belongs to the pancreatic ribonuclease family.
      
 0.415
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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