node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FANCL | FPGT-TNNI3K | ENSP00000385021 | ENSP00000450895 | E3 ubiquitin-protein ligase FANCL; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. | FPGT-TNNI3K readthrough. | 0.446 |
FANCL | GPRC5B | ENSP00000385021 | ENSP00000300571 | E3 ubiquitin-protein ligase FANCL; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. | G-protein coupled receptor family C group 5 member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. | 0.625 |
FANCL | TMEM160 | ENSP00000385021 | ENSP00000253047 | E3 ubiquitin-protein ligase FANCL; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. | Transmembrane protein 160. | 0.446 |
FANCL | TNNI3K | ENSP00000385021 | ENSP00000322251 | E3 ubiquitin-protein ligase FANCL; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.432 |
FANCL | ZNF608 | ENSP00000385021 | ENSP00000307746 | E3 ubiquitin-protein ligase FANCL; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. | Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription. | 0.465 |
FPGT-TNNI3K | FANCL | ENSP00000450895 | ENSP00000385021 | FPGT-TNNI3K readthrough. | E3 ubiquitin-protein ligase FANCL; Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. | 0.446 |
FPGT-TNNI3K | GNPDA2 | ENSP00000450895 | ENSP00000295448 | FPGT-TNNI3K readthrough. | Glucosamine-6-phosphate deaminase 2. | 0.668 |
FPGT-TNNI3K | GPRC5B | ENSP00000450895 | ENSP00000300571 | FPGT-TNNI3K readthrough. | G-protein coupled receptor family C group 5 member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. | 0.586 |
FPGT-TNNI3K | NEGR1 | ENSP00000450895 | ENSP00000350364 | FPGT-TNNI3K readthrough. | Neuronal growth regulator 1; May be involved in cell-adhesion. May function as a trans- neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity); Belongs to the immunoglobulin superfamily. IgLON family. | 0.533 |
FPGT-TNNI3K | SEC16B | ENSP00000450895 | ENSP00000308339 | FPGT-TNNI3K readthrough. | Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes ; Belongs to the SEC16 family. | 0.719 |
FPGT-TNNI3K | TMEM160 | ENSP00000450895 | ENSP00000253047 | FPGT-TNNI3K readthrough. | Transmembrane protein 160. | 0.599 |
FPGT-TNNI3K | TNNI3K | ENSP00000450895 | ENSP00000322251 | FPGT-TNNI3K readthrough. | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.902 |
FPGT-TNNI3K | ZNF608 | ENSP00000450895 | ENSP00000307746 | FPGT-TNNI3K readthrough. | Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription. | 0.570 |
GNPDA2 | FPGT-TNNI3K | ENSP00000295448 | ENSP00000450895 | Glucosamine-6-phosphate deaminase 2. | FPGT-TNNI3K readthrough. | 0.668 |
GNPDA2 | GPRC5B | ENSP00000295448 | ENSP00000300571 | Glucosamine-6-phosphate deaminase 2. | G-protein coupled receptor family C group 5 member B; Unknown. This retinoic acid-inducible G-protein coupled receptor provide evidence for a possible interaction between retinoid and G-protein signaling pathways. | 0.533 |
GNPDA2 | NEGR1 | ENSP00000295448 | ENSP00000350364 | Glucosamine-6-phosphate deaminase 2. | Neuronal growth regulator 1; May be involved in cell-adhesion. May function as a trans- neural growth-promoting factor in regenerative axon sprouting in the mammalian brain (By similarity); Belongs to the immunoglobulin superfamily. IgLON family. | 0.931 |
GNPDA2 | SEC16B | ENSP00000295448 | ENSP00000308339 | Glucosamine-6-phosphate deaminase 2. | Protein transport protein Sec16B; Plays a role in the organization of the endoplasmic reticulum exit sites (ERES), also known as transitional endoplasmic reticulum (tER). Required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. Involved in peroxisome biogenesis. Regulates the transport of peroxisomal biogenesis factors PEX3 and PEX16 from the ER to peroxisomes ; Belongs to the SEC16 family. | 0.872 |
GNPDA2 | TMEM160 | ENSP00000295448 | ENSP00000253047 | Glucosamine-6-phosphate deaminase 2. | Transmembrane protein 160. | 0.604 |
GNPDA2 | TNNI3K | ENSP00000295448 | ENSP00000322251 | Glucosamine-6-phosphate deaminase 2. | Serine/threonine-protein kinase TNNI3K; May play a role in cardiac physiology. Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. | 0.663 |
GNPDA2 | ZNF608 | ENSP00000295448 | ENSP00000307746 | Glucosamine-6-phosphate deaminase 2. | Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription. | 0.541 |