node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD9 | IQCF1 | ENSP00000286918 | ENSP00000307958 | Ankyrin repeat domain 9. | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | 0.572 |
ANKRD9 | ZNF706 | ENSP00000286918 | ENSP00000430823 | Ankyrin repeat domain 9. | Zinc finger protein 706; Transcription repressor involved in the exit of embryonic stem cells (ESCs) from self-renewal. Acts by repressing expression of KLF4. | 0.551 |
CCDC182 | FSCN3 | ENSP00000299415 | ENSP00000265825 | Coiled-coil domain containing 182. | Fascin-3; Acts as an actin bundling protein; Belongs to the fascin family. | 0.442 |
CCDC182 | IQCF1 | ENSP00000299415 | ENSP00000307958 | Coiled-coil domain containing 182. | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | 0.557 |
CCDC182 | KLHL10 | ENSP00000299415 | ENSP00000293303 | Coiled-coil domain containing 182. | Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. | 0.411 |
CCDC83 | FSCN3 | ENSP00000280245 | ENSP00000265825 | Coiled-coil domain containing 83. | Fascin-3; Acts as an actin bundling protein; Belongs to the fascin family. | 0.425 |
CCDC83 | IQCF1 | ENSP00000280245 | ENSP00000307958 | Coiled-coil domain containing 83. | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | 0.628 |
CCDC83 | KLHL10 | ENSP00000280245 | ENSP00000293303 | Coiled-coil domain containing 83. | Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. | 0.470 |
CNBD2 | IQCF1 | ENSP00000340954 | ENSP00000307958 | Cyclic nucleotide-binding domain-containing protein 2; Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm. | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | 0.539 |
CNBD2 | KLHL10 | ENSP00000340954 | ENSP00000293303 | Cyclic nucleotide-binding domain-containing protein 2; Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm. | Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. | 0.467 |
FAR2 | IQCF1 | ENSP00000443291 | ENSP00000307958 | Fatty acyl-CoA reductase 2; Catalyzes the reduction of saturated but not unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. A lower activity can be observed with shorter fatty acyl-CoA substrates. It may play a role in the production of ether lipids/plasmalogens and wax monoesters which synthesis requires fatty alcohols as substrates (By similarity). | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | 0.601 |
FSCN3 | CCDC182 | ENSP00000265825 | ENSP00000299415 | Fascin-3; Acts as an actin bundling protein; Belongs to the fascin family. | Coiled-coil domain containing 182. | 0.442 |
FSCN3 | CCDC83 | ENSP00000265825 | ENSP00000280245 | Fascin-3; Acts as an actin bundling protein; Belongs to the fascin family. | Coiled-coil domain containing 83. | 0.425 |
FSCN3 | IQCF1 | ENSP00000265825 | ENSP00000307958 | Fascin-3; Acts as an actin bundling protein; Belongs to the fascin family. | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | 0.543 |
FSCN3 | KLHL10 | ENSP00000265825 | ENSP00000293303 | Fascin-3; Acts as an actin bundling protein; Belongs to the fascin family. | Kelch-like protein 10; May be a substrate-specific adapter of a CUL3-based E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins during spermatogenesis. | 0.480 |
IQCF1 | ANKRD9 | ENSP00000307958 | ENSP00000286918 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | Ankyrin repeat domain 9. | 0.572 |
IQCF1 | CCDC182 | ENSP00000307958 | ENSP00000299415 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | Coiled-coil domain containing 182. | 0.557 |
IQCF1 | CCDC83 | ENSP00000307958 | ENSP00000280245 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | Coiled-coil domain containing 83. | 0.628 |
IQCF1 | CNBD2 | ENSP00000307958 | ENSP00000340954 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | Cyclic nucleotide-binding domain-containing protein 2; Essential for male fertility. Plays an important role in spermatogenesis and regulates sperm motility by controlling the development of the flagellar bending of sperm. | 0.539 |
IQCF1 | FAR2 | ENSP00000307958 | ENSP00000443291 | IQ domain-containing protein F1; Involved in sperm capacitation and acrosome reaction. | Fatty acyl-CoA reductase 2; Catalyzes the reduction of saturated but not unsaturated C16 or C18 fatty acyl-CoA to fatty alcohols. A lower activity can be observed with shorter fatty acyl-CoA substrates. It may play a role in the production of ether lipids/plasmalogens and wax monoesters which synthesis requires fatty alcohols as substrates (By similarity). | 0.601 |