Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCL21 | KLHL26 | ENSP00000259607 | ENSP00000300976 | C-C motif chemokine 21; Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. | Kelch-like protein 26; Kelch like family member 26. | 0.595 |
| CIB3 | ERICH3 | ENSP00000269878 | ENSP00000322609 | Calcium and integrin binding family member 3. | Glutamate-rich protein 3; Glutamate rich 3. | 0.432 |
| CIB3 | KLHL26 | ENSP00000269878 | ENSP00000300976 | Calcium and integrin binding family member 3. | Kelch-like protein 26; Kelch like family member 26. | 0.517 |
| CIB3 | ODF3L2 | ENSP00000269878 | ENSP00000318029 | Calcium and integrin binding family member 3. | Outer dense fiber of sperm tails 3 like 2. | 0.521 |
| CUL3 | IPP | ENSP00000264414 | ENSP00000379739 | Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin- protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cu [...] | Actin-binding protein IPP; May play a role in organizing the actin cytoskeleton. | 0.614 |
| CUL3 | KLHL12 | ENSP00000264414 | ENSP00000356230 | Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin- protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cu [...] | Kelch-like protein 12; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). The BCR(KLHL12) complex is also involved in neural crest specification: in response to cytosolic calcium increase, interacts w [...] | 0.999 |
| CUL3 | KLHL26 | ENSP00000264414 | ENSP00000300976 | Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin- protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cu [...] | Kelch-like protein 26; Kelch like family member 26. | 0.694 |
| CUL3 | KLHL28 | ENSP00000264414 | ENSP00000347193 | Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin- protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cu [...] | Kelch-like protein 28; Kelch like family member 28. | 0.613 |
| ERICH3 | CIB3 | ENSP00000322609 | ENSP00000269878 | Glutamate-rich protein 3; Glutamate rich 3. | Calcium and integrin binding family member 3. | 0.432 |
| ERICH3 | KLHL26 | ENSP00000322609 | ENSP00000300976 | Glutamate-rich protein 3; Glutamate rich 3. | Kelch-like protein 26; Kelch like family member 26. | 0.566 |
| ERICH3 | ODF3L2 | ENSP00000322609 | ENSP00000318029 | Glutamate-rich protein 3; Glutamate rich 3. | Outer dense fiber of sperm tails 3 like 2. | 0.541 |
| IPP | CUL3 | ENSP00000379739 | ENSP00000264414 | Actin-binding protein IPP; May play a role in organizing the actin cytoskeleton. | Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin- protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cu [...] | 0.614 |
| IPP | KLHL26 | ENSP00000379739 | ENSP00000300976 | Actin-binding protein IPP; May play a role in organizing the actin cytoskeleton. | Kelch-like protein 26; Kelch like family member 26. | 0.523 |
| IPP | KLHL28 | ENSP00000379739 | ENSP00000347193 | Actin-binding protein IPP; May play a role in organizing the actin cytoskeleton. | Kelch-like protein 28; Kelch like family member 28. | 0.710 |
| KLHL12 | CUL3 | ENSP00000356230 | ENSP00000264414 | Kelch-like protein 12; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). The BCR(KLHL12) complex is also involved in neural crest specification: in response to cytosolic calcium increase, interacts w [...] | Cullin-3; Core component of multiple cullin-RING-based BCR (BTB-CUL3- RBX1) E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. BCR complexes and ARIH1 collaborate in tandem to mediate ubiquitination of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin- protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cu [...] | 0.999 |
| KLHL12 | KLHL26 | ENSP00000356230 | ENSP00000300976 | Kelch-like protein 12; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a negative regulator of Wnt signaling pathway and ER-Golgi transport. The BCR(KLHL12) complex is involved in ER-Golgi transport by regulating the size of COPII coats, thereby playing a key role in collagen export, which is required for embryonic stem (ES) cells division: BCR(KLHL12) acts by mediating monoubiquitination of SEC31 (SEC31A or SEC31B). The BCR(KLHL12) complex is also involved in neural crest specification: in response to cytosolic calcium increase, interacts w [...] | Kelch-like protein 26; Kelch like family member 26. | 0.655 |
| KLHL14 | KLHL26 | ENSP00000352314 | ENSP00000300976 | Kelch-like protein 14; Kelch like family member 14. | Kelch-like protein 26; Kelch like family member 26. | 0.519 |
| KLHL14 | KLHL28 | ENSP00000352314 | ENSP00000347193 | Kelch-like protein 14; Kelch like family member 14. | Kelch-like protein 28; Kelch like family member 28. | 0.752 |
| KLHL26 | CCL21 | ENSP00000300976 | ENSP00000259607 | Kelch-like protein 26; Kelch like family member 26. | C-C motif chemokine 21; Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. | 0.595 |
| KLHL26 | CIB3 | ENSP00000300976 | ENSP00000269878 | Kelch-like protein 26; Kelch like family member 26. | Calcium and integrin binding family member 3. | 0.517 |
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