node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KRT2 | KRT31 | ENSP00000310861 | ENSP00000251645 | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). | Keratin, type I cuticular Ha1; Keratin 31. | 0.553 |
KRT2 | KRT6A | ENSP00000310861 | ENSP00000369317 | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). | Keratin, type II cytoskeletal 6A; Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. Belongs to the intermediate filament family. | 0.445 |
KRT2 | KRT76 | ENSP00000310861 | ENSP00000330101 | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). | Keratin, type II cytoskeletal 2 oral; Probably contributes to terminal cornification. Belongs to the intermediate filament family. | 0.445 |
KRT25 | KRT27 | ENSP00000310573 | ENSP00000301656 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | 0.879 |
KRT25 | KRT31 | ENSP00000310573 | ENSP00000251645 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cuticular Ha1; Keratin 31. | 0.549 |
KRT25 | KRT33A | ENSP00000310573 | ENSP00000007735 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family. | 0.539 |
KRT25 | KRT33B | ENSP00000310573 | ENSP00000251646 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | 0.592 |
KRT25 | KRT35 | ENSP00000310573 | ENSP00000377558 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin, type I cuticular Ha5; Keratin 35; Belongs to the intermediate filament family. | 0.720 |
KRT25 | KRTAP3-1 | ENSP00000310573 | ENSP00000375430 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.510 |
KRT25 | KRTAP3-2 | ENSP00000310573 | ENSP00000375429 | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | Keratin-associated protein 3-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.690 |
KRT27 | KRT25 | ENSP00000301656 | ENSP00000310573 | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | 0.879 |
KRT27 | KRT31 | ENSP00000301656 | ENSP00000251645 | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | Keratin, type I cuticular Ha1; Keratin 31. | 0.597 |
KRT27 | KRT33A | ENSP00000301656 | ENSP00000007735 | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | Keratin, type I cuticular Ha3-I; Keratin 33A; Belongs to the intermediate filament family. | 0.624 |
KRT27 | KRT33B | ENSP00000301656 | ENSP00000251646 | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | Keratin, type I cuticular Ha3-II; Keratin 33B; Belongs to the intermediate filament family. | 0.672 |
KRT27 | KRT35 | ENSP00000301656 | ENSP00000377558 | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | Keratin, type I cuticular Ha5; Keratin 35; Belongs to the intermediate filament family. | 0.855 |
KRT27 | KRTAP3-1 | ENSP00000301656 | ENSP00000375430 | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | Keratin-associated protein 3-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.752 |
KRT27 | KRTAP3-2 | ENSP00000301656 | ENSP00000375429 | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | Keratin-associated protein 3-2; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. | 0.823 |
KRT31 | KRT2 | ENSP00000251645 | ENSP00000310861 | Keratin, type I cuticular Ha1; Keratin 31. | Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification. Associated with keratinocyte activation, proliferation and keratinization. Plays a role in the establishment of the epidermal barrier on plantar skin (By similarity). | 0.553 |
KRT31 | KRT25 | ENSP00000251645 | ENSP00000310573 | Keratin, type I cuticular Ha1; Keratin 31. | Keratin, type I cytoskeletal 25; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs) (By similarity). Plays a role in the cytoskeleton organization. | 0.549 |
KRT31 | KRT27 | ENSP00000251645 | ENSP00000301656 | Keratin, type I cuticular Ha1; Keratin 31. | Keratin, type I cytoskeletal 27; Essential for the proper assembly of type I and type II keratin protein complexes and formation of keratin intermediate filaments in the inner root sheath (irs). | 0.597 |