node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LCE2B | LCE2C | ENSP00000357769 | ENSP00000357772 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | 0.999 |
LCE2B | LCE2D | ENSP00000357769 | ENSP00000357773 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum. | 0.999 |
LCE2B | LCE3A | ENSP00000357769 | ENSP00000335006 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | Late cornified envelope protein 3A; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens ; Belongs to the LCE family. | 0.828 |
LCE2B | LCE3D | ENSP00000357769 | ENSP00000357776 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | Late cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family. | 0.905 |
LCE2B | LCE3E | ENSP00000357769 | ENSP00000357778 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | 0.846 |
LCE2B | SPRR1A | ENSP00000357769 | ENSP00000357751 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.683 |
LCE2B | SPRR2B | ENSP00000357769 | ENSP00000357744 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 2A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Belongs to the cornifin (SPRR) family. | 0.791 |
LCE2B | SPRR2D | ENSP00000357769 | ENSP00000357746 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.658 |
LCE2B | SPRR2E | ENSP00000357769 | ENSP00000357740 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 2E; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.718 |
LCE2B | SPRR2G | ENSP00000357769 | ENSP00000357737 | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | Small proline-rich protein 2G; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.851 |
LCE2C | LCE2B | ENSP00000357772 | ENSP00000357769 | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | Late cornified envelope protein 2B; Precursors of the cornified envelope of the stratum corneum. | 0.999 |
LCE2C | LCE2D | ENSP00000357772 | ENSP00000357773 | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | Late cornified envelope protein 2D; Precursors of the cornified envelope of the stratum corneum. | 0.999 |
LCE2C | LCE3A | ENSP00000357772 | ENSP00000335006 | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | Late cornified envelope protein 3A; A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens ; Belongs to the LCE family. | 0.790 |
LCE2C | LCE3D | ENSP00000357772 | ENSP00000357776 | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | Late cornified envelope protein 3D; Precursors of the cornified envelope of the stratum corneum; Belongs to the LCE family. | 0.927 |
LCE2C | LCE3E | ENSP00000357772 | ENSP00000357778 | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | Late cornified envelope protein 3E; Precursors of the cornified envelope of the stratum corneum. | 0.912 |
LCE2C | SPRR1A | ENSP00000357772 | ENSP00000357751 | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | Cornifin-A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.753 |
LCE2C | SPRR2B | ENSP00000357772 | ENSP00000357744 | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | Small proline-rich protein 2A; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane; Belongs to the cornifin (SPRR) family. | 0.841 |
LCE2C | SPRR2D | ENSP00000357772 | ENSP00000357746 | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.761 |
LCE2C | SPRR2E | ENSP00000357772 | ENSP00000357740 | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | Small proline-rich protein 2E; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane. | 0.778 |
LCE2C | SPRR2G | ENSP00000357772 | ENSP00000357737 | Late cornified envelope protein 2C; Precursors of the cornified envelope of the stratum. | Small proline-rich protein 2G; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.844 |