node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ADGRL1 | LRRC37A2 | ENSP00000340688 | ENSP00000459551 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2. | 0.514 |
ADGRL2 | LRRC37A2 | ENSP00000359765 | ENSP00000459551 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2. | 0.514 |
ADGRL3 | LRRC37A2 | ENSP00000422533 | ENSP00000459551 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2. | 0.514 |
ARHGAP27 | ARL17A | ENSP00000403323 | ENSP00000337478 | Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). | 0.583 |
ARHGAP27 | ARL17B | ENSP00000403323 | ENSP00000460539 | Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). | ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B. | 0.560 |
ARHGAP27 | KANSL1 | ENSP00000403323 | ENSP00000387393 | Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). | KAT8 regulatory NSL complex subunit 1; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. | 0.580 |
ARHGAP27 | LRRC37A2 | ENSP00000403323 | ENSP00000459551 | Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). | Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2. | 0.542 |
ARHGAP27 | SPPL2C | ENSP00000403323 | ENSP00000332488 | Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). | Signal peptide peptidase-like 2C; Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane. | 0.480 |
ARL17A | ARHGAP27 | ENSP00000337478 | ENSP00000403323 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). | Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). | 0.583 |
ARL17A | KANSL1 | ENSP00000337478 | ENSP00000387393 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). | KAT8 regulatory NSL complex subunit 1; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. | 0.769 |
ARL17A | LRRC37A2 | ENSP00000337478 | ENSP00000459551 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). | Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2. | 0.742 |
ARL17A | NXPE3 | ENSP00000337478 | ENSP00000273347 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). | NXPE family member 3; Neurexophilin and PC-esterase domain family member 3. | 0.465 |
ARL17A | SPPL2C | ENSP00000337478 | ENSP00000332488 | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). | Signal peptide peptidase-like 2C; Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane. | 0.479 |
ARL17B | ARHGAP27 | ENSP00000460539 | ENSP00000403323 | ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B. | Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). | 0.560 |
ARL17B | KANSL1 | ENSP00000460539 | ENSP00000387393 | ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B. | KAT8 regulatory NSL complex subunit 1; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. | 0.768 |
ARL17B | LRRC37A2 | ENSP00000460539 | ENSP00000459551 | ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B. | Leucine-rich repeat-containing protein 37A2; Leucine rich repeat containing 37 member A2. | 0.744 |
ARL17B | NXPE3 | ENSP00000460539 | ENSP00000273347 | ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B. | NXPE family member 3; Neurexophilin and PC-esterase domain family member 3. | 0.456 |
ARL17B | SPPL2C | ENSP00000460539 | ENSP00000332488 | ADP-ribosylation factor-like protein 17; ADP ribosylation factor like GTPase 17B. | Signal peptide peptidase-like 2C; Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane. | 0.480 |
KANSL1 | ARHGAP27 | ENSP00000387393 | ENSP00000403323 | KAT8 regulatory NSL complex subunit 1; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. | Rho GTPase-activating protein 27; Rho GTPase-activating protein which may be involved in clathrin-mediated endocytosis. GTPase activators for the Rho-type GTPases act by converting them to an inactive GDP-bound state. Has activity toward CDC42 and RAC1 (By similarity). | 0.580 |
KANSL1 | ARL17A | ENSP00000387393 | ENSP00000337478 | KAT8 regulatory NSL complex subunit 1; As part of the NSL complex it is involved in acetylation of nucleosomal histone H4 on several lysine residues and therefore may be involved in the regulation of transcription. | ADP-ribosylation factor-like protein 17; GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus (By similarity). | 0.769 |