node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C11orf49 | EIF3F | ENSP00000367878 | ENSP00000431800 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | 0.710 |
C11orf49 | KIAA1841 | ENSP00000367878 | ENSP00000385579 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Uncharacterized protein KIAA1841; KIAA1841. | 0.627 |
C11orf49 | LRRC49 | ENSP00000367878 | ENSP00000453273 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | 0.906 |
C11orf49 | NICN1 | ENSP00000367878 | ENSP00000273598 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Nicolin-1; Nicolin 1. | 0.818 |
C11orf49 | TBC1D19 | ENSP00000367878 | ENSP00000264866 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | TBC1 domain family member 19; May act as a GTPase-activating protein for Rab family protein(s). | 0.647 |
C11orf49 | TPGS1 | ENSP00000367878 | ENSP00000352265 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.753 |
C11orf49 | TPGS2 | ENSP00000367878 | ENSP00000464780 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Tubulin polyglutamylase complex subunit 2. | 0.854 |
C11orf49 | TTLL1 | ENSP00000367878 | ENSP00000266254 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity). | 0.872 |
EIF3F | C11orf49 | ENSP00000431800 | ENSP00000367878 | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | 0.710 |
EIF3F | LRRC49 | ENSP00000431800 | ENSP00000453273 | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | 0.757 |
EIF3F | TPGS1 | ENSP00000431800 | ENSP00000352265 | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.629 |
KIAA1841 | C11orf49 | ENSP00000385579 | ENSP00000367878 | Uncharacterized protein KIAA1841; KIAA1841. | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | 0.627 |
KIAA1841 | LRRC49 | ENSP00000385579 | ENSP00000453273 | Uncharacterized protein KIAA1841; KIAA1841. | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | 0.805 |
KIAA1841 | NICN1 | ENSP00000385579 | ENSP00000273598 | Uncharacterized protein KIAA1841; KIAA1841. | Nicolin-1; Nicolin 1. | 0.828 |
KIAA1841 | TPGS1 | ENSP00000385579 | ENSP00000352265 | Uncharacterized protein KIAA1841; KIAA1841. | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.610 |
KIAA1841 | TTLL1 | ENSP00000385579 | ENSP00000266254 | Uncharacterized protein KIAA1841; KIAA1841. | Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity). | 0.789 |
LARP6 | LRRC49 | ENSP00000299213 | ENSP00000453273 | La-related protein 6; Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9. | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | 0.543 |
LRRC49 | C11orf49 | ENSP00000453273 | ENSP00000367878 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | 0.906 |
LRRC49 | EIF3F | ENSP00000453273 | ENSP00000431800 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl- tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribos [...] | 0.757 |
LRRC49 | KIAA1841 | ENSP00000453273 | ENSP00000385579 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | Uncharacterized protein KIAA1841; KIAA1841. | 0.805 |