node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTR3C | LRRC61 | ENSP00000252071 | ENSP00000352642 | Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells. | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | 0.607 |
ADGRL1 | LRRC61 | ENSP00000340688 | ENSP00000352642 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | 0.514 |
ADGRL2 | LRRC61 | ENSP00000359765 | ENSP00000352642 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | 0.514 |
ADGRL3 | LRRC61 | ENSP00000422533 | ENSP00000352642 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | 0.514 |
DNAJC27 | FAM184A | ENSP00000264711 | ENSP00000342604 | DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. | Protein FAM184A; Family with sequence similarity 184 member A. | 0.709 |
DNAJC27 | LRRC61 | ENSP00000264711 | ENSP00000352642 | DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | 0.601 |
FAM184A | DNAJC27 | ENSP00000342604 | ENSP00000264711 | Protein FAM184A; Family with sequence similarity 184 member A. | DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. | 0.709 |
FAM184A | LRRC61 | ENSP00000342604 | ENSP00000352642 | Protein FAM184A; Family with sequence similarity 184 member A. | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | 0.613 |
GPR12 | LRRC61 | ENSP00000384932 | ENSP00000352642 | G-protein coupled receptor 12; Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production; Belongs to the G-protein coupled receptor 1 family. | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | 0.528 |
KRBA1 | LRRC61 | ENSP00000418647 | ENSP00000352642 | Protein KRBA1; KRAB-A domain containing 1. | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | 0.637 |
KRBA1 | ZBED6CL | ENSP00000418647 | ENSP00000343242 | Protein KRBA1; KRAB-A domain containing 1. | ZBED6 C-terminal-like protein; ZBED6 C-terminal like. | 0.581 |
LRRC61 | ACTR3C | ENSP00000352642 | ENSP00000252071 | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | Actin-related protein 3C; May play a role in the suppression of metastatic potential in lung adenoma carcinoma cells. | 0.607 |
LRRC61 | ADGRL1 | ENSP00000352642 | ENSP00000340688 | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). | 0.514 |
LRRC61 | ADGRL2 | ENSP00000352642 | ENSP00000359765 | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.514 |
LRRC61 | ADGRL3 | ENSP00000352642 | ENSP00000422533 | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. | 0.514 |
LRRC61 | DNAJC27 | ENSP00000352642 | ENSP00000264711 | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | DnaJ homolog subfamily C member 27; GTPase which can activate the MEK/ERK pathway and induce cell transformation when overexpressed. May act as a nuclear scaffold for MAPK1, probably by association with MAPK1 nuclear export signal leading to enhanced ERK1/ERK2 signaling. | 0.601 |
LRRC61 | FAM184A | ENSP00000352642 | ENSP00000342604 | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | Protein FAM184A; Family with sequence similarity 184 member A. | 0.613 |
LRRC61 | GPR12 | ENSP00000352642 | ENSP00000384932 | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | G-protein coupled receptor 12; Promotes neurite outgrowth and blocks myelin inhibition in neurons (By similarity). Receptor with constitutive G(s) signaling activity that stimulates cyclic AMP production; Belongs to the G-protein coupled receptor 1 family. | 0.528 |
LRRC61 | KRBA1 | ENSP00000352642 | ENSP00000418647 | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | Protein KRBA1; KRAB-A domain containing 1. | 0.637 |
LRRC61 | ZBED6CL | ENSP00000352642 | ENSP00000343242 | Leucine-rich repeat-containing protein 61; Leucine rich repeat containing 61. | ZBED6 C-terminal-like protein; ZBED6 C-terminal like. | 0.936 |