STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LSMEM2Leucine rich single-pass membrane protein 2. (164 aa)    
Predicted Functional Partners:
SPACA1
Sperm acrosome membrane-associated protein 1; Plays a role in acrosome expansion and establishment of normal sperm morphology during spermatogenesis (By similarity). Important for male fertility.
    
   0.540
C5orf24
UPF0461 protein C5orf24; Chromosome 5 open reading frame 24; Belongs to the UPF0461 family.
      
 0.506
ZNF551
Zinc finger protein 551; May be involved in transcriptional regulation.
      
 0.505
ADPRHL1
[Protein ADP-ribosylarginine] hydrolase-like protein 1; ADP-ribosylhydrolase like 1.
   
  
 0.502
KLHL34
Kelch-like protein 34; Kelch like family member 34.
   
  
 0.495
WDR47
WD repeat domain 47.
      
 0.484
LSMEM1
Leucine rich single-pass membrane protein 1.
   
   0.446
TASOR2
Protein TASOR 2; Transcription activation suppressor family member 2; Belongs to the TASOR family.
      
 0.446
KLHL23
Kelch-like protein 23; Kelch like family member 23.
      
 0.418
IFRD2
Interferon related developmental regulator 2.
   
  
 0.406
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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