node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFF3 | MCTP2 | ENSP00000386834 | ENSP00000350377 | AF4/FMR2 family member 3; Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double- stranded DNA; Belongs to the AF4 family. | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | 0.477 |
ANO4 | MCTP2 | ENSP00000376703 | ENSP00000350377 | Anoctamin-4; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (By similarity). | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | 0.499 |
ANO4 | OR6C75 | ENSP00000376703 | ENSP00000493430 | Anoctamin-4; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (By similarity). | Olfactory receptor 6C75; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.434 |
CPNE5 | FRMPD1 | ENSP00000244751 | ENSP00000444411 | Copine-5; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (By similarity). Plays a role in dendrite formation by melanocytes ; Belongs to the copine family. | FERM and PDZ domain-containing protein 1; Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1. | 0.498 |
CPNE5 | MCTP2 | ENSP00000244751 | ENSP00000350377 | Copine-5; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (By similarity). Plays a role in dendrite formation by melanocytes ; Belongs to the copine family. | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | 0.472 |
CPNE5 | NCALD | ENSP00000244751 | ENSP00000379256 | Copine-5; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (By similarity). Plays a role in dendrite formation by melanocytes ; Belongs to the copine family. | Neurocalcin-delta; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions; Belongs to the recoverin family. | 0.492 |
CPNE5 | TMEM51 | ENSP00000244751 | ENSP00000365176 | Copine-5; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (By similarity). Plays a role in dendrite formation by melanocytes ; Belongs to the copine family. | Transmembrane protein 51. | 0.468 |
FRMPD1 | CPNE5 | ENSP00000444411 | ENSP00000244751 | FERM and PDZ domain-containing protein 1; Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1. | Copine-5; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (By similarity). Plays a role in dendrite formation by melanocytes ; Belongs to the copine family. | 0.498 |
FRMPD1 | MCTP2 | ENSP00000444411 | ENSP00000350377 | FERM and PDZ domain-containing protein 1; Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1. | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | 0.560 |
FRMPD1 | NCALD | ENSP00000444411 | ENSP00000379256 | FERM and PDZ domain-containing protein 1; Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1. | Neurocalcin-delta; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions; Belongs to the recoverin family. | 0.445 |
FRMPD1 | TMEM51 | ENSP00000444411 | ENSP00000365176 | FERM and PDZ domain-containing protein 1; Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1. | Transmembrane protein 51. | 0.502 |
MCTP2 | AFF3 | ENSP00000350377 | ENSP00000386834 | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | AF4/FMR2 family member 3; Putative transcription activator that may function in lymphoid development and oncogenesis. Binds, in vitro, to double- stranded DNA; Belongs to the AF4 family. | 0.477 |
MCTP2 | ANO4 | ENSP00000350377 | ENSP00000376703 | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | Anoctamin-4; Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (By similarity). | 0.499 |
MCTP2 | CPNE5 | ENSP00000350377 | ENSP00000244751 | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | Copine-5; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (By similarity). Plays a role in dendrite formation by melanocytes ; Belongs to the copine family. | 0.472 |
MCTP2 | FRMPD1 | ENSP00000350377 | ENSP00000444411 | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | FERM and PDZ domain-containing protein 1; Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1. | 0.560 |
MCTP2 | NCALD | ENSP00000350377 | ENSP00000379256 | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | Neurocalcin-delta; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions; Belongs to the recoverin family. | 0.462 |
MCTP2 | OR6C75 | ENSP00000350377 | ENSP00000493430 | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | Olfactory receptor 6C75; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.511 |
MCTP2 | RGMA | ENSP00000350377 | ENSP00000452126 | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | Repulsive guidance molecule A; Member of the repulsive guidance molecule (RGM) family that performs several functions in the developing and adult nervous system. Regulates cephalic neural tube closure, inhibits neurite outgrowth and cortical neuron branching, and the formation of mature synapses. Binding to its receptor NEO1/neogenin induces activation of RHOA- ROCK1/Rho-kinase signaling pathway through UNC5B-ARHGEF12/LARG- PTK2/FAK1 cascade, leading to collapse of the neuronal growth cone and neurite outgrowth inhibition. Furthermore, RGMA binding to NEO1/neogenin leads to HRAS inacti [...] | 0.580 |
MCTP2 | TMEM182 | ENSP00000350377 | ENSP00000394178 | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | Transmembrane protein 182. | 0.472 |
MCTP2 | TMEM51 | ENSP00000350377 | ENSP00000365176 | Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family. | Transmembrane protein 51. | 0.457 |