Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CSMD1 | MDGA2 | ENSP00000489225 | ENSP00000405456 | CUB and sushi domain-containing protein 1; Potential suppressor of squamous cell carcinomas. | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | 0.515 |
| DCLK1 | KCNQ3 | ENSP00000353846 | ENSP00000373648 | Serine/threonine-protein kinase DCLK1; Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. | Potassium voltage-gated channel subfamily KQT member 3; Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Therefore, it is important in the regulation of neuronal excitability. | 0.425 |
| DCLK1 | MDGA2 | ENSP00000353846 | ENSP00000405456 | Serine/threonine-protein kinase DCLK1; Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | 0.486 |
| FN1 | MDGA2 | ENSP00000346839 | ENSP00000405456 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | 0.497 |
| KCNQ3 | DCLK1 | ENSP00000373648 | ENSP00000353846 | Potassium voltage-gated channel subfamily KQT member 3; Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Therefore, it is important in the regulation of neuronal excitability. | Serine/threonine-protein kinase DCLK1; Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. | 0.425 |
| KCNQ3 | MDGA2 | ENSP00000373648 | ENSP00000405456 | Potassium voltage-gated channel subfamily KQT member 3; Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Therefore, it is important in the regulation of neuronal excitability. | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | 0.475 |
| MDGA2 | CSMD1 | ENSP00000405456 | ENSP00000489225 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | CUB and sushi domain-containing protein 1; Potential suppressor of squamous cell carcinomas. | 0.515 |
| MDGA2 | DCLK1 | ENSP00000405456 | ENSP00000353846 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | Serine/threonine-protein kinase DCLK1; Probable kinase that may be involved in a calcium-signaling pathway controlling neuronal migration in the developing brain. May also participate in functions of the mature nervous system; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. CaMK subfamily. | 0.486 |
| MDGA2 | FN1 | ENSP00000405456 | ENSP00000346839 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts. | 0.497 |
| MDGA2 | KCNQ3 | ENSP00000405456 | ENSP00000373648 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | Potassium voltage-gated channel subfamily KQT member 3; Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. Therefore, it is important in the regulation of neuronal excitability. | 0.475 |
| MDGA2 | NLGN1 | ENSP00000405456 | ENSP00000392500 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | Neuroligin-1; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep. | 0.788 |
| MDGA2 | NLGN2 | ENSP00000405456 | ENSP00000305288 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | Neuroligin-2; Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors). Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Promotes clustering of postsynaptic LHFPL4 (By similarity). Modulates signaling by inhibitory synapses [...] | 0.839 |
| MDGA2 | NLGN3 | ENSP00000405456 | ENSP00000351591 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity); Belongs to the type-B carboxylesterase/lipase family. | 0.679 |
| MDGA2 | NLGN4X | ENSP00000405456 | ENSP00000370483 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | Neuroligin-4, X-linked; Putative neuronal cell surface protein involved in cell-cell- interactions; Belongs to the type-B carboxylesterase/lipase family. | 0.626 |
| MDGA2 | PDE4D | ENSP00000405456 | ENSP00000345502 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | cAMP-specific 3',5'-cyclic phosphodiesterase 4D; Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. | 0.501 |
| MDGA2 | SPPL2C | ENSP00000405456 | ENSP00000332488 | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | Signal peptide peptidase-like 2C; Intramembrane-cleaving aspartic protease (I-CLiP) that may be able to cleave type II membrane signal peptides in the hydrophobic plane of the membrane. | 0.576 |
| NLGN1 | MDGA2 | ENSP00000392500 | ENSP00000405456 | Neuroligin-1; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep. | MAM domain-containing glycosylphosphatidylinositol anchor protein 2; May be involved in cell-cell interactions. | 0.788 |
| NLGN1 | NLGN2 | ENSP00000392500 | ENSP00000305288 | Neuroligin-1; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep. | Neuroligin-2; Transmembrane scaffolding protein involved in cell-cell interactions via its interactions with neurexin family members. Mediates cell-cell interactions both in neurons and in other types of cells, such as Langerhans beta cells. Plays a role in synapse function and synaptic signal transmission, especially via gamma-aminobutyric acid receptors (GABA(A) receptors). Functions by recruiting and clustering synaptic proteins. Promotes clustering of postsynaptic GABRG2 and GPHN. Promotes clustering of postsynaptic LHFPL4 (By similarity). Modulates signaling by inhibitory synapses [...] | 0.704 |
| NLGN1 | NLGN3 | ENSP00000392500 | ENSP00000351591 | Neuroligin-1; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep. | Neuroligin-3; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and may mediate its effects by clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. May also play a role in glia-glia or glia-neuron interactions in the developing peripheral nervous system (By similarity); Belongs to the type-B carboxylesterase/lipase family. | 0.799 |
| NLGN1 | NLGN4X | ENSP00000392500 | ENSP00000370483 | Neuroligin-1; Cell surface protein involved in cell-cell-interactions via its interactions with neurexin family members. Plays a role in synapse function and synaptic signal transmission, and probably mediates its effects by recruiting and clustering other synaptic proteins. May promote the initial formation of synapses, but is not essential for this. In vitro, triggers the de novo formation of presynaptic structures. May be involved in specification of excitatory synapses. Required to maintain wakefulness quality and normal synchrony of cerebral cortex activity during wakefulness and sleep. | Neuroligin-4, X-linked; Putative neuronal cell surface protein involved in cell-cell- interactions; Belongs to the type-B carboxylesterase/lipase family. | 0.548 |
page 1 of 2