node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AP2B1 | AP2M1 | ENSP00000483185 | ENSP00000403362 | AP-2 complex subunit beta; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but [...] | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | 0.999 |
AP2B1 | MEA1 | ENSP00000483185 | ENSP00000495612 | AP-2 complex subunit beta; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but [...] | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | 0.677 |
AP2M1 | AP2B1 | ENSP00000403362 | ENSP00000483185 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | AP-2 complex subunit beta; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but [...] | 0.999 |
AP2M1 | MEA1 | ENSP00000403362 | ENSP00000495612 | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | 0.650 |
BRK1 | MEA1 | ENSP00000432472 | ENSP00000495612 | Protein BRICK1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | 0.763 |
GOLGA3 | MEA1 | ENSP00000204726 | ENSP00000495612 | Golgin subfamily A member 3; Golgi auto-antigen; probably involved in maintaining Golgi structure. | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | 0.887 |
GOLGA3 | SPATA16 | ENSP00000204726 | ENSP00000341765 | Golgin subfamily A member 3; Golgi auto-antigen; probably involved in maintaining Golgi structure. | Spermatogenesis-associated protein 16; Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion. | 0.847 |
KLHDC3 | MEA1 | ENSP00000313995 | ENSP00000495612 | Kelch domain-containing protein 3; May be involved in meiotic recombination process. | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | 0.944 |
KLHDC3 | PPP2R5D | ENSP00000313995 | ENSP00000417963 | Kelch domain-containing protein 3; May be involved in meiotic recombination process. | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment; Belongs to the phosphatase 2A regulatory subunit B56 family. | 0.949 |
KLHL1 | MEA1 | ENSP00000367075 | ENSP00000495612 | Kelch-like protein 1; May play a role in organizing the actin cytoskeleton of the brain cells. | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | 0.761 |
KLHL1 | PPP2R5D | ENSP00000367075 | ENSP00000417963 | Kelch-like protein 1; May play a role in organizing the actin cytoskeleton of the brain cells. | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment; Belongs to the phosphatase 2A regulatory subunit B56 family. | 0.495 |
MEA1 | AP2B1 | ENSP00000495612 | ENSP00000483185 | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | AP-2 complex subunit beta; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but [...] | 0.677 |
MEA1 | AP2M1 | ENSP00000495612 | ENSP00000403362 | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] | 0.650 |
MEA1 | BRK1 | ENSP00000495612 | ENSP00000432472 | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | Protein BRICK1; Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). | 0.763 |
MEA1 | GOLGA3 | ENSP00000495612 | ENSP00000204726 | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | Golgin subfamily A member 3; Golgi auto-antigen; probably involved in maintaining Golgi structure. | 0.887 |
MEA1 | KLHDC3 | ENSP00000495612 | ENSP00000313995 | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | Kelch domain-containing protein 3; May be involved in meiotic recombination process. | 0.944 |
MEA1 | KLHL1 | ENSP00000495612 | ENSP00000367075 | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | Kelch-like protein 1; May play a role in organizing the actin cytoskeleton of the brain cells. | 0.761 |
MEA1 | NDUFS7 | ENSP00000495612 | ENSP00000233627 | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. | 0.759 |
MEA1 | PPP2R5D | ENSP00000495612 | ENSP00000417963 | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment; Belongs to the phosphatase 2A regulatory subunit B56 family. | 0.934 |
MEA1 | SPATA16 | ENSP00000495612 | ENSP00000341765 | Male-enhanced antigen 1; May play an important role in spermatogenesis and/or testis development. | Spermatogenesis-associated protein 16; Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion. | 0.830 |