STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MFSD6Major facilitator superfamily domain-containing protein 6; Major facilitator superfamily domain containing 6 (791 aa)    
Predicted Functional Partners:
ZNF384
Zinc finger protein 384; Transcription factor that binds the consensus DNA sequence [GC]AAAAA. Seems to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1 (By similarity); Belongs to the krueppel C2H2-type zinc-finger protein family
   
    0.816
FAM73A
Mitoguardin 1; Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family
      
 0.727
NAB1
NGFI-A-binding protein 1; Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2
      
 0.721
CSGALNACT2
Chondroitin sulfate n-acetylgalactosaminyltransferase 1/2; Chondroitin sulfate N-acetylgalactosaminyltransferase 2; Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains
   
  
 0.714
C19orf12
Protein C19orf12; Chromosome 19 open reading frame 12
      
 0.699
TMEM194B
Nuclear envelope integral membrane protein 2; Transmembrane protein 194B; Belongs to the NEMP family
      
 0.663
TMEM180
Major facilitator superfamily domain containing 13a; Transmembrane protein 180
      
 0.659
MFSD12
Major facilitator superfamily domain-containing protein 12; Major facilitator superfamily domain containing 12
   
  
 0.649
MFSD10
Major facilitator superfamily domain-containing protein 10; Confers cellular resistance to apoptosis induced by the non-steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump
      
 0.644
MFSD9
Major facilitator superfamily domain-containing protein 9; Major facilitator superfamily domain containing 9
      
 0.643
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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