close STRING Database User Survey
Please help us improve further — take a moment to fill our brief user survey.
 
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRPL1239S ribosomal protein L12, mitochondrial; Associates with mitochondrial RNA polymerase to activate transcription; Belongs to the bacterial ribosomal protein bL12 family (198 aa)    
Predicted Functional Partners:
ICT1
Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes
  
 0.999
MRPL17
39S ribosomal protein L17, mitochondrial; Mitochondrial ribosomal protein L17
  
 0.998
MRPL13
39S ribosomal protein L13, mitochondrial; Mitochondrial ribosomal protein L13; Belongs to the universal ribosomal protein uL13 family
  
 0.998
MRPL11
39S ribosomal protein L11, mitochondrial; Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family
  
 0.998
MRPL4
39S ribosomal protein L4, mitochondrial; Mitochondrial ribosomal protein L4; Belongs to the universal ribosomal protein uL4 family
  
 0.997
MRPL3
39S ribosomal protein L3, mitochondrial; Mitochondrial ribosomal protein L3
  
 0.997
MRPL10
39S ribosomal protein L10, mitochondrial; Mitochondrial ribosomal protein L10; Belongs to the universal ribosomal protein uL10 family
   
 0.997
MRPL19
39S ribosomal protein L19, mitochondrial; Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family
  
 0.997
MRPL47
39S ribosomal protein L47, mitochondrial; Belongs to the universal ribosomal protein uL29 family
   
 0.997
MRPL32
39S ribosomal protein L32, mitochondrial; Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family
  
 0.996
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (6%) [HD]