MRPL37 protein (human) - STRING interaction network

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Score

MRPL37

Mitochondrial ribosomal protein L37; Belongs to the mitochondrion-specific ribosomal protein mL37 family. (483 aa)

Predicted Functional Partners:

MRPS30

0.992

MRPL24

0.989

MRPL2

0.989

MRPL41

0.987

MRPL11

0.986

MRPL47

0.986

MRPL28

0.986

GADD45GIP1

0.983

MRPL9

0.983

MRPL40

0.982

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GADD45GIP1	MRPL11	ENSP00000323065	ENSP00000308897	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	0.990
GADD45GIP1	MRPL2	ENSP00000323065	ENSP00000373404	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family.	0.959
GADD45GIP1	MRPL24	ENSP00000323065	ENSP00000354525	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family.	0.972
GADD45GIP1	MRPL28	ENSP00000323065	ENSP00000497004	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L28.	0.989
GADD45GIP1	MRPL37	ENSP00000323065	ENSP00000473980	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L37; Belongs to the mitochondrion-specific ribosomal protein mL37 family.	0.983
GADD45GIP1	MRPL40	ENSP00000323065	ENSP00000333401	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family.	0.986
GADD45GIP1	MRPL41	ENSP00000323065	ENSP00000360498	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.	0.986
GADD45GIP1	MRPL47	ENSP00000323065	ENSP00000417602	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L47; Belongs to the universal ribosomal protein uL29 family.	0.980
GADD45GIP1	MRPL9	ENSP00000323065	ENSP00000357823	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein L9.	0.982
GADD45GIP1	MRPS30	ENSP00000323065	ENSP00000424328	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	Mitochondrial ribosomal protein S30.	0.983
MRPL11	GADD45GIP1	ENSP00000308897	ENSP00000323065	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	Growth arrest and DNA damage-inducible proteins-interacting protein 1; Acts as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis; Belongs to the mitochondrion-specific ribosomal protei [...]	0.990
MRPL11	MRPL2	ENSP00000308897	ENSP00000373404	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	Mitochondrial ribosomal protein L2; Belongs to the universal ribosomal protein uL2 family.	0.996
MRPL11	MRPL24	ENSP00000308897	ENSP00000354525	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	Mitochondrial ribosomal protein L24; Belongs to the universal ribosomal protein uL24 family.	0.998
MRPL11	MRPL28	ENSP00000308897	ENSP00000497004	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	Mitochondrial ribosomal protein L28.	0.934
MRPL11	MRPL37	ENSP00000308897	ENSP00000473980	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	Mitochondrial ribosomal protein L37; Belongs to the mitochondrion-specific ribosomal protein mL37 family.	0.986
MRPL11	MRPL40	ENSP00000308897	ENSP00000333401	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family.	0.985
MRPL11	MRPL41	ENSP00000308897	ENSP00000360498	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins.	0.998
MRPL11	MRPL47	ENSP00000308897	ENSP00000417602	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	Mitochondrial ribosomal protein L47; Belongs to the universal ribosomal protein uL29 family.	0.998
MRPL11	MRPL9	ENSP00000308897	ENSP00000357823	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	Mitochondrial ribosomal protein L9.	0.998
MRPL11	MRPS30	ENSP00000308897	ENSP00000424328	Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family.	Mitochondrial ribosomal protein S30.	0.982