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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRPL5439S ribosomal protein L54, mitochondrial; Mitochondrial ribosomal protein L54 (138 aa)    
Predicted Functional Partners:
MRPL27
39S ribosomal protein L27, mitochondrial; Mitochondrial ribosomal protein L27
   
  0.997
MRPL17
39S ribosomal protein L17, mitochondrial; Mitochondrial ribosomal protein L17
   
  0.997
MRPL11
39S ribosomal protein L11, mitochondrial; Mitochondrial ribosomal protein L11; Belongs to the universal ribosomal protein uL11 family
   
 0.996
MRPL47
39S ribosomal protein L47, mitochondrial; Belongs to the universal ribosomal protein uL29 family
   
 0.996
MRPL40
39S ribosomal protein L40, mitochondrial; Mitochondrial ribosomal protein L40; Belongs to the mitochondrion-specific ribosomal protein mL40 family
   
 0.995
MRPL41
39S ribosomal protein L41, mitochondrial; Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins
   
 0.995
MRPL32
39S ribosomal protein L32, mitochondrial; Mitochondrial ribosomal protein L32; Belongs to the bacterial ribosomal protein bL32 family
   
 0.994
MRPL43
39S ribosomal protein L43, mitochondrial; Mitochondrial ribosomal protein L43
   
  0.993
MRPL20
39S ribosomal protein L20, mitochondrial; Mitochondrial ribosomal protein L20
   
  0.993
MRPL46
39S ribosomal protein L46, mitochondrial; Mitochondrial ribosomal protein L46; Belongs to the mitochondrion-specific ribosomal protein mL46 family
   
 0.992
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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