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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MRRFRibosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity) (262 aa)    
Predicted Functional Partners:
MRPS9
28S ribosomal protein S9, mitochondrial; Mitochondrial ribosomal protein S9
  
 
 0.986
MRPL20
39S ribosomal protein L20, mitochondrial; Mitochondrial ribosomal protein L20
  
 
 0.983
MRPS16
28S ribosomal protein S16, mitochondrial; Mitochondrial ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family
  
 
 0.981
ICT1
Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes
  
 
 0.980
GFM1
Elongation factor G, mitochondrial; Mitochondrial GTPase that catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A- site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome. Does not mediate the disassembly of ribosomes from messenger RNA at the termination of mit [...]
  
 
 0.978
MRPL19
39S ribosomal protein L19, mitochondrial; Mitochondrial ribosomal protein L19; Belongs to the bacterial ribosomal protein bL19 family
  
 
 0.977
MRPL27
39S ribosomal protein L27, mitochondrial; Mitochondrial ribosomal protein L27
  
 
 0.972
MRPS10
28S ribosomal protein S10, mitochondrial; Mitochondrial ribosomal protein S10; Belongs to the universal ribosomal protein uS10 family
  
 
 0.970
MRPL21
39S ribosomal protein L21, mitochondrial; Mitochondrial ribosomal protein L21
  
 
 0.969
MRPL9
39S ribosomal protein L9, mitochondrial; Mitochondrial ribosomal protein L9
   
 
 0.967
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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