node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GRPEL1 | MTMR11 | ENSP00000264954 | ENSP00000391668 | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Belongs to the GrpE family. | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.436 |
LRGUK | MTMR10 | ENSP00000285928 | ENSP00000402537 | Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. | Myotubularin related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.495 |
LRGUK | MTMR11 | ENSP00000285928 | ENSP00000391668 | Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.495 |
LRGUK | MTMR12 | ENSP00000285928 | ENSP00000371577 | Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. | Myotubularin-related protein 12; Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (By similarity). Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.495 |
MTMR10 | LRGUK | ENSP00000402537 | ENSP00000285928 | Myotubularin related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. | 0.495 |
MTMR10 | MTMR11 | ENSP00000402537 | ENSP00000391668 | Myotubularin related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.448 |
MTMR10 | MTMR12 | ENSP00000402537 | ENSP00000371577 | Myotubularin related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Myotubularin-related protein 12; Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (By similarity). Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.432 |
MTMR11 | GRPEL1 | ENSP00000391668 | ENSP00000264954 | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | GrpE protein homolog 1, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner (By similarity). Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Belongs to the GrpE family. | 0.436 |
MTMR11 | LRGUK | ENSP00000391668 | ENSP00000285928 | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. | 0.495 |
MTMR11 | MTMR10 | ENSP00000391668 | ENSP00000402537 | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Myotubularin related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.448 |
MTMR11 | MTMR12 | ENSP00000391668 | ENSP00000371577 | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Myotubularin-related protein 12; Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (By similarity). Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.478 |
MTMR11 | NT5DC1 | ENSP00000391668 | ENSP00000326858 | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 5'-nucleotidase domain containing 1. | 0.422 |
MTMR11 | OR10H2 | ENSP00000391668 | ENSP00000306095 | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Olfactory receptor 10H2; Odorant receptor; Belongs to the G-protein coupled receptor 1 family. | 0.447 |
MTMR11 | SF3B4 | ENSP00000391668 | ENSP00000271628 | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Splicing factor 3B subunit 4; Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex. SF3B4 has been found in complex 'B' and 'C' as well. Belongs also to the minor U12- dependent spliceosome, which is involved in the splicing of rare clas [...] | 0.486 |
MTMR11 | TMEM184B | ENSP00000391668 | ENSP00000354441 | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Transmembrane protein 184B; May activate the MAP kinase signaling pathway. Belongs to the TMEM184 family. | 0.423 |
MTMR11 | TPST1 | ENSP00000391668 | ENSP00000302413 | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Protein-tyrosine sulfotransferase 1; Catalyzes the O-sulfation of tyrosine residues within acidic motifs of polypeptides, using 3'-phosphoadenylyl sulfate (PAPS) as cosubstrate; Belongs to the protein sulfotransferase family. | 0.402 |
MTMR11 | ZNF182 | ENSP00000391668 | ENSP00000380165 | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Zinc finger protein 182; May be involved in transcriptional regulation. | 0.424 |
MTMR12 | LRGUK | ENSP00000371577 | ENSP00000285928 | Myotubularin-related protein 12; Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (By similarity). Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Leucine-rich repeat and guanylate kinase domain-containing protein; Involved in multiple aspects of sperm assembly including acrosome attachment, shaping of the sperm head and in the early aspects of axoneme development. Not essential for primary cilium biogenesis. | 0.495 |
MTMR12 | MTMR10 | ENSP00000371577 | ENSP00000402537 | Myotubularin-related protein 12; Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (By similarity). Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Myotubularin related protein 10; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.432 |
MTMR12 | MTMR11 | ENSP00000371577 | ENSP00000391668 | Myotubularin-related protein 12; Acts as an adapter for the myotubularin-related phosphatases. Regulates phosphatase MTM1 protein stability and possibly its intracellular location. By stabilizing MTM1 protein levels, required for skeletal muscle maintenance but not for myogenesis (By similarity). Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | Myotubularin related protein 11; Belongs to the protein-tyrosine phosphatase family. Non- receptor class myotubularin subfamily. | 0.478 |