node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MUC1 | MUC13 | ENSP00000484824 | ENSP00000485028 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | 0.943 |
MUC1 | MUC15 | ENSP00000484824 | ENSP00000431983 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-15; May play a role in the cell adhesion to the extracellular matrix. | 0.970 |
MUC1 | MUC16 | ENSP00000484824 | ENSP00000381008 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. | 0.951 |
MUC1 | MUC2 | ENSP00000484824 | ENSP00000494061 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-2; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. | 0.972 |
MUC1 | MUC20 | ENSP00000484824 | ENSP00000414350 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. | 0.953 |
MUC1 | MUC21 | ENSP00000484824 | ENSP00000365473 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-21; Mucin 21, cell surface associated. | 0.819 |
MUC1 | MUC3A | ENSP00000484824 | ENSP00000368771 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-3A; Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling. | 0.882 |
MUC1 | MUC5B | ENSP00000484824 | ENSP00000436812 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-5B; Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. | 0.969 |
MUC1 | MUC6 | ENSP00000484824 | ENSP00000406861 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-6; May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. | 0.977 |
MUC1 | MUC7 | ENSP00000484824 | ENSP00000407422 | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili. | 0.964 |
MUC13 | MUC1 | ENSP00000485028 | ENSP00000484824 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-1 subunit alpha; The alpha subunit has cell adhesive properties. Can act both as an adhesion and an anti-adhesion protein. May provide a protective layer on epithelial cells against bacterial and enzyme attack. | 0.943 |
MUC13 | MUC15 | ENSP00000485028 | ENSP00000431983 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-15; May play a role in the cell adhesion to the extracellular matrix. | 0.940 |
MUC13 | MUC16 | ENSP00000485028 | ENSP00000381008 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-16; Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. | 0.911 |
MUC13 | MUC2 | ENSP00000485028 | ENSP00000494061 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-2; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. | 0.961 |
MUC13 | MUC20 | ENSP00000485028 | ENSP00000414350 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression. | 0.949 |
MUC13 | MUC21 | ENSP00000485028 | ENSP00000365473 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-21; Mucin 21, cell surface associated. | 0.915 |
MUC13 | MUC3A | ENSP00000485028 | ENSP00000368771 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-3A; Major glycoprotein component of a variety of mucus gels. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. May be involved in ligand binding and intracellular signaling. | 0.920 |
MUC13 | MUC5B | ENSP00000485028 | ENSP00000436812 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-5B; Gel-forming mucin that is thought to contribute to the lubricating and viscoelastic properties of whole saliva and cervical mucus. | 0.926 |
MUC13 | MUC6 | ENSP00000485028 | ENSP00000406861 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-6; May provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. | 0.899 |
MUC13 | MUC7 | ENSP00000485028 | ENSP00000407422 | Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling. | Mucin-7; May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili. | 0.942 |