node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTN2 | MYH3 | ENSP00000355537 | ENSP00000464317 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | Myosin-3; Muscle contraction. | 0.951 |
ACTN2 | MYH4 | ENSP00000355537 | ENSP00000255381 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | Myosin-4; Muscle contraction. | 0.801 |
ACTN2 | MYH6 | ENSP00000355537 | ENSP00000386041 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | Myosin-6; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.973 |
ACTN2 | MYL1 | ENSP00000355537 | ENSP00000307280 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.907 |
ACTN2 | MYL3 | ENSP00000355537 | ENSP00000499406 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.878 |
ACTN2 | MYLPF | ENSP00000355537 | ENSP00000325239 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | Myosin light chain, phosphorylatable, fast skeletal muscle. | 0.764 |
ACTN2 | TNNI1 | ENSP00000355537 | ENSP00000354488 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.906 |
ACTN2 | TNNI2 | ENSP00000355537 | ENSP00000371336 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.695 |
ACTN2 | TNNT3 | ENSP00000355537 | ENSP00000370975 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.865 |
ACTN2 | TPM2 | ENSP00000355537 | ENSP00000496494 | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | Tropomyosin beta chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. | 0.760 |
MYH3 | ACTN2 | ENSP00000464317 | ENSP00000355537 | Myosin-3; Muscle contraction. | Alpha-actinin-2; F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein. | 0.951 |
MYH3 | MYH4 | ENSP00000464317 | ENSP00000255381 | Myosin-3; Muscle contraction. | Myosin-4; Muscle contraction. | 0.927 |
MYH3 | MYH6 | ENSP00000464317 | ENSP00000386041 | Myosin-3; Muscle contraction. | Myosin-6; Muscle contraction; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.900 |
MYH3 | MYL1 | ENSP00000464317 | ENSP00000307280 | Myosin-3; Muscle contraction. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.957 |
MYH3 | MYL3 | ENSP00000464317 | ENSP00000499406 | Myosin-3; Muscle contraction. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.888 |
MYH3 | MYLPF | ENSP00000464317 | ENSP00000325239 | Myosin-3; Muscle contraction. | Myosin light chain, phosphorylatable, fast skeletal muscle. | 0.954 |
MYH3 | TNNI1 | ENSP00000464317 | ENSP00000354488 | Myosin-3; Muscle contraction. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.953 |
MYH3 | TNNI2 | ENSP00000464317 | ENSP00000371336 | Myosin-3; Muscle contraction. | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.974 |
MYH3 | TNNT3 | ENSP00000464317 | ENSP00000370975 | Myosin-3; Muscle contraction. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.965 |
MYH3 | TPM2 | ENSP00000464317 | ENSP00000496494 | Myosin-3; Muscle contraction. | Tropomyosin beta chain; Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization. | 0.959 |