node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DHRS7B | NATD1 | ENSP00000378887 | ENSP00000478388 | Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Protein NATD1; N-acetyltransferase domain containing 1. | 0.517 |
DHRS7B | TMEM11 | ENSP00000378887 | ENSP00000319992 | Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Transmembrane protein 11, mitochondrial; Plays a role in mitochondrial morphogenesis. Belongs to the TMEM11 family. | 0.538 |
DRC3 | DRG2 | ENSP00000382140 | ENSP00000225729 | Dynein regulatory complex subunit 3; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes; Belongs to the DRC3 family. | Developmentally-regulated GTP-binding protein 2; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation. | 0.437 |
DRC3 | NATD1 | ENSP00000382140 | ENSP00000478388 | Dynein regulatory complex subunit 3; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes; Belongs to the DRC3 family. | Protein NATD1; N-acetyltransferase domain containing 1. | 0.514 |
DRG2 | DRC3 | ENSP00000225729 | ENSP00000382140 | Developmentally-regulated GTP-binding protein 2; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation. | Dynein regulatory complex subunit 3; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes; Belongs to the DRC3 family. | 0.437 |
DRG2 | NATD1 | ENSP00000225729 | ENSP00000478388 | Developmentally-regulated GTP-binding protein 2; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation. | Protein NATD1; N-acetyltransferase domain containing 1. | 0.414 |
FKBP7 | NATD1 | ENSP00000413152 | ENSP00000478388 | Peptidyl-prolyl cis-trans isomerase FKBP7; PPIases accelerate the folding of proteins during protein synthesis. | Protein NATD1; N-acetyltransferase domain containing 1. | 0.401 |
GID8 | NATD1 | ENSP00000266069 | ENSP00000478388 | Glucose-induced degradation protein 8 homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation ; Belongs to the GID8 family. | Protein NATD1; N-acetyltransferase domain containing 1. | 0.422 |
NATD1 | DHRS7B | ENSP00000478388 | ENSP00000378887 | Protein NATD1; N-acetyltransferase domain containing 1. | Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.517 |
NATD1 | DRC3 | ENSP00000478388 | ENSP00000382140 | Protein NATD1; N-acetyltransferase domain containing 1. | Dynein regulatory complex subunit 3; Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes; Belongs to the DRC3 family. | 0.514 |
NATD1 | DRG2 | ENSP00000478388 | ENSP00000225729 | Protein NATD1; N-acetyltransferase domain containing 1. | Developmentally-regulated GTP-binding protein 2; Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation. | 0.414 |
NATD1 | FKBP7 | ENSP00000478388 | ENSP00000413152 | Protein NATD1; N-acetyltransferase domain containing 1. | Peptidyl-prolyl cis-trans isomerase FKBP7; PPIases accelerate the folding of proteins during protein synthesis. | 0.401 |
NATD1 | GID8 | ENSP00000478388 | ENSP00000266069 | Protein NATD1; N-acetyltransferase domain containing 1. | Glucose-induced degradation protein 8 homolog; Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. Acts as a positive regulator of Wnt signaling pathway by promoting beta-catenin (CTNNB1) nuclear accumulation ; Belongs to the GID8 family. | 0.422 |
NATD1 | NT5M | ENSP00000478388 | ENSP00000373674 | Protein NATD1; N-acetyltransferase domain containing 1. | 5'(3')-deoxyribonucleotidase, mitochondrial; Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. | 0.403 |
NATD1 | TMEM11 | ENSP00000478388 | ENSP00000319992 | Protein NATD1; N-acetyltransferase domain containing 1. | Transmembrane protein 11, mitochondrial; Plays a role in mitochondrial morphogenesis. Belongs to the TMEM11 family. | 0.471 |
NT5M | NATD1 | ENSP00000373674 | ENSP00000478388 | 5'(3')-deoxyribonucleotidase, mitochondrial; Dephosphorylates specifically the 5' and 2'(3')-phosphates of uracil and thymine deoxyribonucleotides, and so protects mitochondrial DNA replication from excess dTTP. Has only marginal activity towards dIMP and dGMP. | Protein NATD1; N-acetyltransferase domain containing 1. | 0.403 |
TMEM11 | DHRS7B | ENSP00000319992 | ENSP00000378887 | Transmembrane protein 11, mitochondrial; Plays a role in mitochondrial morphogenesis. Belongs to the TMEM11 family. | Dehydrogenase/reductase SDR family member 7B; Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.538 |
TMEM11 | NATD1 | ENSP00000319992 | ENSP00000478388 | Transmembrane protein 11, mitochondrial; Plays a role in mitochondrial morphogenesis. Belongs to the TMEM11 family. | Protein NATD1; N-acetyltransferase domain containing 1. | 0.471 |