node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKS4B | PLEKHH3 | ENSP00000308772 | ENSP00000468678 | Ankyrin repeat and SAM domain-containing protein 4B; As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. Plays a role in assembly of the complex. May play a role in cellular response to endoplasmic reticulum stress (By similarity). | Pleckstrin homology, MyTH4 and FERM domain containing H3. | 0.474 |
ASB15 | GRIFIN | ENSP00000397655 | ENSP00000481185 | Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Grifin; Galectin-related inter-fiber protein. | 0.408 |
ASB15 | PLEKHH3 | ENSP00000397655 | ENSP00000468678 | Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Pleckstrin homology, MyTH4 and FERM domain containing H3. | 0.507 |
ASB15 | WDR49 | ENSP00000397655 | ENSP00000311343 | Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | WD repeat domain 49. | 0.475 |
FAM151A | PLEKHH3 | ENSP00000306888 | ENSP00000468678 | Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family. | Pleckstrin homology, MyTH4 and FERM domain containing H3. | 0.466 |
GRIFIN | ASB15 | ENSP00000481185 | ENSP00000397655 | Grifin; Galectin-related inter-fiber protein. | Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.408 |
GRIFIN | PLEKHH3 | ENSP00000481185 | ENSP00000468678 | Grifin; Galectin-related inter-fiber protein. | Pleckstrin homology, MyTH4 and FERM domain containing H3. | 0.482 |
GRIFIN | WDR49 | ENSP00000481185 | ENSP00000311343 | Grifin; Galectin-related inter-fiber protein. | WD repeat domain 49. | 0.498 |
MYO19 | PLEKHH3 | ENSP00000479518 | ENSP00000468678 | Unconventional myosin-XIX; Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane. Motor protein that moves towards the plus-end of actin filaments (By similarity). Required for mitochondrial inheritance during mitosis. May be involved in mitochondrial transport or positioning. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Pleckstrin homology, MyTH4 and FERM domain containing H3. | 0.525 |
MYO1A | MYO1C | ENSP00000393392 | ENSP00000496954 | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Unconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in st [...] | 0.909 |
MYO1A | PLEKHH3 | ENSP00000393392 | ENSP00000468678 | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | Pleckstrin homology, MyTH4 and FERM domain containing H3. | 0.558 |
MYO1C | MYO1A | ENSP00000496954 | ENSP00000393392 | Unconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in st [...] | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.909 |
MYO1C | PLEKHH3 | ENSP00000496954 | ENSP00000468678 | Unconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in st [...] | Pleckstrin homology, MyTH4 and FERM domain containing H3. | 0.584 |
PLEKHH3 | ANKS4B | ENSP00000468678 | ENSP00000308772 | Pleckstrin homology, MyTH4 and FERM domain containing H3. | Ankyrin repeat and SAM domain-containing protein 4B; As part of the intermicrovillar adhesion complex/IMAC plays a role in epithelial brush border differentiation, controlling microvilli organization and length. Plays a role in assembly of the complex. May play a role in cellular response to endoplasmic reticulum stress (By similarity). | 0.474 |
PLEKHH3 | ASB15 | ENSP00000468678 | ENSP00000397655 | Pleckstrin homology, MyTH4 and FERM domain containing H3. | Ankyrin repeat and SOCS box protein 15; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.507 |
PLEKHH3 | FAM151A | ENSP00000468678 | ENSP00000306888 | Pleckstrin homology, MyTH4 and FERM domain containing H3. | Protein FAM151A; Family with sequence similarity 151 member A; Belongs to the FAM151 family. | 0.466 |
PLEKHH3 | GRIFIN | ENSP00000468678 | ENSP00000481185 | Pleckstrin homology, MyTH4 and FERM domain containing H3. | Grifin; Galectin-related inter-fiber protein. | 0.482 |
PLEKHH3 | MYO19 | ENSP00000468678 | ENSP00000479518 | Pleckstrin homology, MyTH4 and FERM domain containing H3. | Unconventional myosin-XIX; Actin-based motor molecule with ATPase activity that localizes to the mitochondrion outer membrane. Motor protein that moves towards the plus-end of actin filaments (By similarity). Required for mitochondrial inheritance during mitosis. May be involved in mitochondrial transport or positioning. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.525 |
PLEKHH3 | MYO1A | ENSP00000468678 | ENSP00000393392 | Pleckstrin homology, MyTH4 and FERM domain containing H3. | Unconventional myosin-Ia; Involved in directing the movement of organelles along actin filaments; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.558 |
PLEKHH3 | MYO1C | ENSP00000468678 | ENSP00000496954 | Pleckstrin homology, MyTH4 and FERM domain containing H3. | Unconventional myosin-Ic; Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Involved in glucose transporter recycling in response to insulin by regulating movement of intracellular GLUT4-containing vesicles to the plasma membrane. Component of the hair cell's (the sensory cells of the inner ear) adaptation-motor complex. Acts as a mediator of adaptation of mechanoelectrical transduction in st [...] | 0.584 |