node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANKRD22 | ANKRD46 | ENSP00000360998 | ENSP00000429015 | Ankyrin repeat domain 22. | Ankyrin repeat domain 46. | 0.445 |
ANKRD22 | ASB5 | ENSP00000360998 | ENSP00000296525 | Ankyrin repeat domain 22. | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity); Belongs to the ankyrin SOCS box (ASB) family. | 0.413 |
ANKRD22 | MTPN | ENSP00000360998 | ENSP00000376800 | Ankyrin repeat domain 22. | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Belongs to the myotrophin family. | 0.416 |
ANKRD22 | NFKBIA | ENSP00000360998 | ENSP00000216797 | Ankyrin repeat domain 22. | NF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. | 0.478 |
ANKRD22 | POTEB3 | ENSP00000360998 | ENSP00000483103 | Ankyrin repeat domain 22. | POTE ankyrin domain family member B3. | 0.485 |
ANKRD22 | POTEC | ENSP00000360998 | ENSP00000351856 | Ankyrin repeat domain 22. | POTE ankyrin domain family member C. | 0.491 |
ANKRD46 | ANKRD22 | ENSP00000429015 | ENSP00000360998 | Ankyrin repeat domain 46. | Ankyrin repeat domain 22. | 0.445 |
ANKRD46 | ASB11 | ENSP00000429015 | ENSP00000417914 | Ankyrin repeat domain 46. | Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | 0.427 |
ANKRD46 | ASB12 | ENSP00000429015 | ENSP00000355195 | Ankyrin repeat domain 46. | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.402 |
ANKRD46 | ASB5 | ENSP00000429015 | ENSP00000296525 | Ankyrin repeat domain 46. | Ankyrin repeat and SOCS box protein 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity); Belongs to the ankyrin SOCS box (ASB) family. | 0.414 |
ANKRD46 | MTPN | ENSP00000429015 | ENSP00000376800 | Ankyrin repeat domain 46. | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Belongs to the myotrophin family. | 0.436 |
ANKRD46 | POTEB3 | ENSP00000429015 | ENSP00000483103 | Ankyrin repeat domain 46. | POTE ankyrin domain family member B3. | 0.490 |
ANKRD46 | POTEC | ENSP00000429015 | ENSP00000351856 | Ankyrin repeat domain 46. | POTE ankyrin domain family member C. | 0.493 |
ASB11 | ANKRD46 | ENSP00000417914 | ENSP00000429015 | Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | Ankyrin repeat domain 46. | 0.427 |
ASB11 | MTPN | ENSP00000417914 | ENSP00000376800 | Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | Myotrophin; Promotes dimerization of NF-kappa-B subunits and regulates NF-kappa-B transcription factor activity (By similarity). Plays a role in the regulation of the growth of actin filaments. Inhibits the activity of the F-actin-capping protein complex formed by the CAPZA1 and CAPZB heterodimer. Promotes growth of cardiomyocytes, but not cardiomyocyte proliferation. Promotes cardiac muscle hypertrophy. Belongs to the myotrophin family. | 0.449 |
ASB11 | NFKBIA | ENSP00000417914 | ENSP00000216797 | Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | NF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. | 0.492 |
ASB11 | POTEB3 | ENSP00000417914 | ENSP00000483103 | Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | POTE ankyrin domain family member B3. | 0.491 |
ASB11 | POTEC | ENSP00000417914 | ENSP00000351856 | Ankyrin repeat and SOCS box protein 11; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins; Belongs to the ankyrin SOCS box (ASB) family. | POTE ankyrin domain family member C. | 0.495 |
ASB12 | ANKRD46 | ENSP00000355195 | ENSP00000429015 | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Ankyrin repeat domain 46. | 0.402 |
ASB12 | NFKBIA | ENSP00000355195 | ENSP00000216797 | Ankyrin repeat and SOCS box protein 12; Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | NF-kappa-B inhibitor alpha; Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. | 0.466 |