node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACTR10 | ACTR8 | ENSP00000254286 | ENSP00000336842 | Actin related protein 10; Belongs to the actin family. | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. | 0.536 |
ACTR10 | CAP1 | ENSP00000254286 | ENSP00000361883 | Actin related protein 10; Belongs to the actin family. | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family. | 0.425 |
ACTR10 | DCTN2 | ENSP00000254286 | ENSP00000408910 | Actin related protein 10; Belongs to the actin family. | Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development. | 0.999 |
ACTR10 | PFN4 | ENSP00000254286 | ENSP00000322170 | Actin related protein 10; Belongs to the actin family. | Profilin-4; Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Does not bind to actin , contrary to other family members; Belongs to the profilin family. | 0.435 |
ACTR10 | POTEI | ENSP00000254286 | ENSP00000392718 | Actin related protein 10; Belongs to the actin family. | POTE ankyrin domain family member I; In the N-terminal section; belongs to the POTE family. | 0.458 |
ACTR8 | ACTR10 | ENSP00000336842 | ENSP00000254286 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. | Actin related protein 10; Belongs to the actin family. | 0.536 |
ACTR8 | POTEI | ENSP00000336842 | ENSP00000392718 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. | POTE ankyrin domain family member I; In the N-terminal section; belongs to the POTE family. | 0.459 |
C20orf203 | POTEI | ENSP00000495424 | ENSP00000392718 | Uncharacterized protein C20orf203; Chromosome 20 open reading frame 203. | POTE ankyrin domain family member I; In the N-terminal section; belongs to the POTE family. | 0.452 |
CAP1 | ACTR10 | ENSP00000361883 | ENSP00000254286 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family. | Actin related protein 10; Belongs to the actin family. | 0.425 |
CAP1 | CAP2 | ENSP00000361883 | ENSP00000229922 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family. | Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family. | 0.836 |
CAP1 | MYL1 | ENSP00000361883 | ENSP00000307280 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.526 |
CAP1 | PFN4 | ENSP00000361883 | ENSP00000322170 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family. | Profilin-4; Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Does not bind to actin , contrary to other family members; Belongs to the profilin family. | 0.849 |
CAP1 | POTEI | ENSP00000361883 | ENSP00000392718 | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family. | POTE ankyrin domain family member I; In the N-terminal section; belongs to the POTE family. | 0.499 |
CAP2 | CAP1 | ENSP00000229922 | ENSP00000361883 | Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family. | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family. | 0.836 |
CAP2 | PFN4 | ENSP00000229922 | ENSP00000322170 | Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family. | Profilin-4; Binds to phosphatidylinositol 3-phosphate (PtdIns(3)P), phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), phosphatidylinositol 4-phosphate (PtdIns(4)P) and phosphatidic acid (PA). Does not bind to actin , contrary to other family members; Belongs to the profilin family. | 0.730 |
CAP2 | POTEI | ENSP00000229922 | ENSP00000392718 | Adenylyl cyclase-associated protein 2; May have a regulatory bifunctional role; Belongs to the CAP family. | POTE ankyrin domain family member I; In the N-terminal section; belongs to the POTE family. | 0.550 |
DCTN2 | ACTR10 | ENSP00000408910 | ENSP00000254286 | Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development. | Actin related protein 10; Belongs to the actin family. | 0.999 |
DCTN2 | POTEI | ENSP00000408910 | ENSP00000392718 | Dynactin subunit 2; Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. Involved in anchoring microtubules to centrosomes. May play a role in synapse formation during brain development. | POTE ankyrin domain family member I; In the N-terminal section; belongs to the POTE family. | 0.476 |
MYL1 | CAP1 | ENSP00000307280 | ENSP00000361883 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Adenylyl cyclase-associated protein 1; Directly regulates filament dynamics and has been implicated in a number of complex developmental and morphological processes, including mRNA localization and the establishment of cell polarity; Belongs to the CAP family. | 0.526 |
MYL1 | POTEI | ENSP00000307280 | ENSP00000392718 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | POTE ankyrin domain family member I; In the N-terminal section; belongs to the POTE family. | 0.466 |