STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRAC1PRAC1 small nuclear protein (57 aa)    
Predicted Functional Partners:
PRAC2
PRAC2 small nuclear protein
   
  
 0.939
HOXB13
Homeobox protein Hox-B13; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis; HOXL subclass homeoboxes
   
  
 0.932
ZNF540
Zinc finger protein 540; May act as a transcriptional repressor; Zinc fingers C2H2-type
      
 0.583
PCDHAC1
Protocadherin alpha-C1; Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain; Clustered protocadherins
      
 0.564
FAM78A
Protein FAM78A; Family with sequence similarity 78 member A; Belongs to the FAM78 family
      
 0.557
ZNF671
Zinc finger protein 671; May be involved in transcriptional regulation; Zinc fingers C2H2-type
      
 0.540
RIMS4
Regulating synaptic membrane exocytosis protein 4; Regulates synaptic membrane exocytosis
      
 0.532
FAM150A
ALK and LTK ligand 1; Ligand for receptor tyrosine kinase LTK and perhaps receptor tyrosine kinase ALK; activation of ALK is reported conflictingly
      
 0.475
ZNF154
Zinc finger protein 154; May be involved in transcriptional regulation; Zinc fingers C2H2-type
      
 0.473
ERICH4
Glutamate-rich protein 4; Glutamate rich 4
      
 0.426
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo sapiens, human, man
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