node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LUC7L | LUC7L3 | ENSP00000293872 | ENSP00000376919 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain. | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. | 0.803 |
LUC7L | PNN | ENSP00000293872 | ENSP00000216832 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain. | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation [...] | 0.470 |
LUC7L | PPIG | ENSP00000293872 | ENSP00000260970 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain. | Peptidyl-prolyl cis-trans isomerase G; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing. | 0.591 |
LUC7L | PRPF38A | ENSP00000293872 | ENSP00000257181 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain. | Pre-mRNA-splicing factor 38A; Involved in pre-mRNA splicing as a component of the spliceosome. | 0.427 |
LUC7L | PRPF38B | ENSP00000293872 | ENSP00000359042 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain. | Pre-mRNA-splicing factor 38B; May be required for pre-mRNA splicing. | 0.660 |
LUC7L | RBM25 | ENSP00000293872 | ENSP00000261973 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain. | RNA-binding protein 25; RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7 [...] | 0.997 |
LUC7L | SRSF11 | ENSP00000293872 | ENSP00000359988 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain. | Serine/arginine-rich splicing factor 11; May function in pre-mRNA splicing. | 0.605 |
LUC7L | ZC3H18 | ENSP00000293872 | ENSP00000416951 | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain. | Zinc finger CCCH-type containing 18. | 0.608 |
LUC7L3 | LUC7L | ENSP00000376919 | ENSP00000293872 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain. | 0.803 |
LUC7L3 | PNN | ENSP00000376919 | ENSP00000216832 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation [...] | 0.796 |
LUC7L3 | PRPF38B | ENSP00000376919 | ENSP00000359042 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. | Pre-mRNA-splicing factor 38B; May be required for pre-mRNA splicing. | 0.674 |
LUC7L3 | RBM25 | ENSP00000376919 | ENSP00000261973 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. | RNA-binding protein 25; RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7 [...] | 0.989 |
LUC7L3 | SLTM | ENSP00000376919 | ENSP00000369887 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. | SAFB-like transcription modulator; When overexpressed, acts as a general inhibitor of transcription that eventually leads to apoptosis. | 0.402 |
LUC7L3 | SRSF11 | ENSP00000376919 | ENSP00000359988 | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. | Serine/arginine-rich splicing factor 11; May function in pre-mRNA splicing. | 0.915 |
PNN | LUC7L | ENSP00000216832 | ENSP00000293872 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation [...] | Putative RNA-binding protein Luc7-like 1; May bind to RNA via its Arg/Ser-rich domain. | 0.470 |
PNN | LUC7L3 | ENSP00000216832 | ENSP00000376919 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation [...] | Luc7-like protein 3; Binds cAMP regulatory element DNA sequence. May play a role in RNA splicing. | 0.796 |
PNN | PPIG | ENSP00000216832 | ENSP00000260970 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation [...] | Peptidyl-prolyl cis-trans isomerase G; PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding. May be implicated in the folding, transport, and assembly of proteins. May play an important role in the regulation of pre-mRNA splicing. | 0.906 |
PNN | PRPF38B | ENSP00000216832 | ENSP00000359042 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation [...] | Pre-mRNA-splicing factor 38B; May be required for pre-mRNA splicing. | 0.713 |
PNN | RBM25 | ENSP00000216832 | ENSP00000261973 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation [...] | RNA-binding protein 25; RNA-binding protein that acts as a regulator of alternative pre-mRNA splicing. Involved in apoptotic cell death through the regulation of the apoptotic factor BCL2L1 isoform expression. Modulates the ratio of proapoptotic BCL2L1 isoform S to antiapoptotic BCL2L1 isoform L mRNA expression. When overexpressed, stimulates proapoptotic BCL2L1 isoform S 5'-splice site (5'-ss) selection, whereas its depletion caused the accumulation of antiapoptotic BCL2L1 isoform L. Promotes BCL2L1 isoform S 5'-ss usage through the 5'-CGGGCA-3' RNA sequence. Its association with LUC7 [...] | 0.812 |
PNN | SRSF11 | ENSP00000216832 | ENSP00000359988 | Pinin; Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation [...] | Serine/arginine-rich splicing factor 11; May function in pre-mRNA splicing. | 0.942 |