STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRR18Proline-rich protein 18; Proline rich 18. (295 aa)    
Predicted Functional Partners:
SFT2D1
Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family.
      
 0.651
C6orf118
Uncharacterized protein C6orf118; Chromosome 6 open reading frame 118.
   
  
 0.630
FAM43B
Protein FAM43B; Family with sequence similarity 43 member B; Belongs to the FAM43 family.
   
  
 0.558
SHISA8
Protein shisa-8; May regulate trafficking and current kinetics of AMPA-type glutamate receptor (AMPAR) at synapses; Belongs to the shisa family.
   
  
 0.495
WRNIP1
ATPase WRNIP1; Functions as a modulator of initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis. In the presence of ATP, stimulation of DNA polymerase delta-mediated DNA synthesis is decreased. Plays also a role in the innate immune defense against viruses. Stabilizes the RIG-I/DDX58 dsRNA interaction and promotes RIG- I/DDX58 'Lys-63'-linked polyubiquitination. In turn, RIG-I/DDX58 transmits the signal through mitochondrial MAVS.
      
 0.479
TCP10L2
T-complex protein 10A homolog 2; T-complex 10 like 2, pseudogene; Belongs to the TCP10 family.
      
 0.473
RNFT2
Ring finger protein, transmembrane 2.
   
  
 0.441
CMTM5
CKLF like MARVEL transmembrane domain containing 5; Belongs to the chemokine-like factor family.
   
  
 0.435
OPALIN
Opalin; Central nervous system-specific myelin protein that increase myelin genes expression during oligodendrocyte differentiation. Promotes oligodendrocyte terminal differentiation.
   
    0.417
TMEM88B
Transmembrane protein 88B.
   
  
 0.409
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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