Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GSPT1 | GSPT2 | ENSP00000398131 | ENSP00000341247 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity). Stimulates the activity of ETF1 (By similarity). Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular gen [...] | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. | 0.991 |
| GSPT1 | RBM12B | ENSP00000398131 | ENSP00000382239 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity). Stimulates the activity of ETF1 (By similarity). Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular gen [...] | RNA binding motif protein 12B. | 0.486 |
| GSPT2 | GSPT1 | ENSP00000341247 | ENSP00000398131 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity). Stimulates the activity of ETF1 (By similarity). Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular gen [...] | 0.991 |
| GSPT2 | RBM12B | ENSP00000341247 | ENSP00000382239 | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. | RNA binding motif protein 12B. | 0.479 |
| RBM10 | RBM12B | ENSP00000328848 | ENSP00000382239 | RNA-binding protein 10; May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins. | RNA binding motif protein 12B. | 0.561 |
| RBM12B | GSPT1 | ENSP00000382239 | ENSP00000398131 | RNA binding motif protein 12B. | Eukaryotic peptide chain release factor GTP-binding subunit ERF3A; Involved in translation termination in response to the termination codons UAA, UAG and UGA (By similarity). Stimulates the activity of ETF1 (By similarity). Involved in regulation of mammalian cell growth. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Required for SHFL-mediated translation termination which inhibits programmed ribosomal frameshifting (-1PRF) of mRNA from viruses and cellular gen [...] | 0.486 |
| RBM12B | GSPT2 | ENSP00000382239 | ENSP00000341247 | RNA binding motif protein 12B. | Eukaryotic peptide chain release factor GTP-binding subunit ERF3B; Involved in translation termination in response to the termination codons UAA, UAG and UGA. May play a role as a potent stimulator of the release factor activity of ETF1. Exhibits GTPase activity, which is ribosome- and ETF1-dependent. May play a role in cell cycle progression. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons. | 0.479 |
| RBM12B | RBM10 | ENSP00000382239 | ENSP00000328848 | RNA binding motif protein 12B. | RNA-binding protein 10; May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity). May bind to specific miRNA hairpins. | 0.561 |
| RBM12B | RNF20 | ENSP00000382239 | ENSP00000373772 | RNA binding motif protein 12B. | E3 ubiquitin-protein ligase BRE1A; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradi [...] | 0.483 |
| RBM12B | TBC1D22A | ENSP00000382239 | ENSP00000336724 | RNA binding motif protein 12B. | TBC1 domain family member 22A; May act as a GTPase-activating protein for Rab family protein(s). | 0.495 |
| RBM12B | TRABD | ENSP00000382239 | ENSP00000379173 | RNA binding motif protein 12B. | TraB domain-containing protein; TraB domain containing. | 0.510 |
| RBM12B | TSKS | ENSP00000382239 | ENSP00000246801 | RNA binding motif protein 12B. | Testis-specific serine kinase substrate; May play a role in testicular physiology, most probably in the process of spermatogenesis or spermatid development. | 0.590 |
| RBM12B | YLPM1 | ENSP00000382239 | ENSP00000324463 | RNA binding motif protein 12B. | YLP motif-containing protein 1; Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation. | 0.481 |
| RBM12B | ZNF398 | ENSP00000382239 | ENSP00000420418 | RNA binding motif protein 12B. | Zinc finger protein 398; Functions as a transcriptional activator. | 0.487 |
| RBM12B | ZNF510 | ENSP00000382239 | ENSP00000364379 | RNA binding motif protein 12B. | Zinc finger protein 510; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.472 |
| RNF20 | RBM12B | ENSP00000373772 | ENSP00000382239 | E3 ubiquitin-protein ligase BRE1A; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradi [...] | RNA binding motif protein 12B. | 0.483 |
| TBC1D22A | RBM12B | ENSP00000336724 | ENSP00000382239 | TBC1 domain family member 22A; May act as a GTPase-activating protein for Rab family protein(s). | RNA binding motif protein 12B. | 0.495 |
| TBC1D22A | TRABD | ENSP00000336724 | ENSP00000379173 | TBC1 domain family member 22A; May act as a GTPase-activating protein for Rab family protein(s). | TraB domain-containing protein; TraB domain containing. | 0.564 |
| TRABD | RBM12B | ENSP00000379173 | ENSP00000382239 | TraB domain-containing protein; TraB domain containing. | RNA binding motif protein 12B. | 0.510 |
| TRABD | TBC1D22A | ENSP00000379173 | ENSP00000336724 | TraB domain-containing protein; TraB domain containing. | TBC1 domain family member 22A; May act as a GTPase-activating protein for Rab family protein(s). | 0.564 |
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