node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATP6V0A1 | SERINC2 | ENSP00000264649 | ENSP00000362814 | V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity). | Serine incorporator 2; Belongs to the TDE1 family. | 0.483 |
GPN3 | MPZL2 | ENSP00000442770 | ENSP00000278937 | GPN-loop GTPase 3; Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.429 |
GPN3 | SERINC2 | ENSP00000442770 | ENSP00000362814 | GPN-loop GTPase 3; Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. | Serine incorporator 2; Belongs to the TDE1 family. | 0.448 |
KIAA0040 | SERINC2 | ENSP00000462172 | ENSP00000362814 | Uncharacterized protein KIAA0040; KIAA0040. | Serine incorporator 2; Belongs to the TDE1 family. | 0.581 |
LRRC14 | SERINC2 | ENSP00000292524 | ENSP00000362814 | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily. | Serine incorporator 2; Belongs to the TDE1 family. | 0.462 |
MPZL2 | GPN3 | ENSP00000278937 | ENSP00000442770 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | GPN-loop GTPase 3; Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. | 0.429 |
MPZL2 | SERINC2 | ENSP00000278937 | ENSP00000362814 | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | Serine incorporator 2; Belongs to the TDE1 family. | 0.430 |
NKAIN1 | SERINC2 | ENSP00000362841 | ENSP00000362814 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1. | Serine incorporator 2; Belongs to the TDE1 family. | 0.514 |
NKAIN1 | ZCCHC17 | ENSP00000362841 | ENSP00000480986 | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1. | Nucleolar protein of 40 kDa; Zinc finger CCHC-type containing 17. | 0.467 |
SERINC2 | ATP6V0A1 | ENSP00000362814 | ENSP00000264649 | Serine incorporator 2; Belongs to the TDE1 family. | V-type proton ATPase 116 kDa subunit a isoform 1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity). | 0.483 |
SERINC2 | GPN3 | ENSP00000362814 | ENSP00000442770 | Serine incorporator 2; Belongs to the TDE1 family. | GPN-loop GTPase 3; Small GTPase required for proper localization of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. | 0.448 |
SERINC2 | KIAA0040 | ENSP00000362814 | ENSP00000462172 | Serine incorporator 2; Belongs to the TDE1 family. | Uncharacterized protein KIAA0040; KIAA0040. | 0.581 |
SERINC2 | LRRC14 | ENSP00000362814 | ENSP00000292524 | Serine incorporator 2; Belongs to the TDE1 family. | Leucine-rich repeat-containing protein 14; Negatively regulates Toll-like receptor-mediated NF-kappa-B signaling by disrupting IKK core complex formation through interaction with IKBKB; Belongs to the PRAME family. LRRC14 subfamily. | 0.462 |
SERINC2 | MPZL2 | ENSP00000362814 | ENSP00000278937 | Serine incorporator 2; Belongs to the TDE1 family. | Myelin protein zero-like protein 2; Mediates homophilic cell-cell adhesion. | 0.430 |
SERINC2 | NKAIN1 | ENSP00000362814 | ENSP00000362841 | Serine incorporator 2; Belongs to the TDE1 family. | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1; Sodium/potassium transporting ATPase interacting 1. | 0.514 |
SERINC2 | STOM | ENSP00000362814 | ENSP00000286713 | Serine incorporator 2; Belongs to the TDE1 family. | Erythrocyte band 7 integral membrane protein; Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity; Belongs to the band 7/mec-2 family. | 0.432 |
SERINC2 | TMBIM6 | ENSP00000362814 | ENSP00000389277 | Serine incorporator 2; Belongs to the TDE1 family. | Bax inhibitor 1; Suppressor of apoptosis. Modulates unfolded protein response signaling. Modulates ER calcium homeostasis by acting as a calcium-leak channel. Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (By similarity). | 0.452 |
SERINC2 | TTC14 | ENSP00000362814 | ENSP00000296015 | Serine incorporator 2; Belongs to the TDE1 family. | Tetratricopeptide repeat domain 14; Belongs to the TTC14 family. | 0.486 |
SERINC2 | ZCCHC17 | ENSP00000362814 | ENSP00000480986 | Serine incorporator 2; Belongs to the TDE1 family. | Nucleolar protein of 40 kDa; Zinc finger CCHC-type containing 17. | 0.439 |
STOM | SERINC2 | ENSP00000286713 | ENSP00000362814 | Erythrocyte band 7 integral membrane protein; Regulates ion channel activity and transmembrane ion transport. Regulates ASIC2 and ASIC3 channel activity; Belongs to the band 7/mec-2 family. | Serine incorporator 2; Belongs to the TDE1 family. | 0.432 |