node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C6orf118 | PRR18 | ENSP00000230301 | ENSP00000319590 | Uncharacterized protein C6orf118; Chromosome 6 open reading frame 118. | Proline-rich protein 18; Proline rich 18. | 0.630 |
C6orf118 | SFT2D1 | ENSP00000230301 | ENSP00000354590 | Uncharacterized protein C6orf118; Chromosome 6 open reading frame 118. | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | 0.593 |
C6orf118 | UNC93A | ENSP00000230301 | ENSP00000230256 | Uncharacterized protein C6orf118; Chromosome 6 open reading frame 118. | Unc-93 homolog A. | 0.418 |
CTDNEP1 | MAL2 | ENSP00000460683 | ENSP00000479708 | CTD nuclear envelope phosphatase 1; Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and [...] | Protein MAL2; Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway. | 0.408 |
CTDNEP1 | SFT2D1 | ENSP00000460683 | ENSP00000354590 | CTD nuclear envelope phosphatase 1; Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and [...] | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | 0.497 |
FAM43A | SFT2D1 | ENSP00000371397 | ENSP00000354590 | Protein FAM43A; Family with sequence similarity 43 member A; Belongs to the FAM43 family. | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | 0.496 |
GOLT1A | SFT2D1 | ENSP00000308535 | ENSP00000354590 | Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex; Belongs to the GOT1 family. | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | 0.519 |
GOLT1A | SFT2D3 | ENSP00000308535 | ENSP00000310803 | Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex; Belongs to the GOT1 family. | Vesicle transport protein SFT2C; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | 0.545 |
MAL2 | CTDNEP1 | ENSP00000479708 | ENSP00000460683 | Protein MAL2; Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway. | CTD nuclear envelope phosphatase 1; Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and [...] | 0.408 |
MAL2 | SFT2D1 | ENSP00000479708 | ENSP00000354590 | Protein MAL2; Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway. | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | 0.446 |
PRR18 | C6orf118 | ENSP00000319590 | ENSP00000230301 | Proline-rich protein 18; Proline rich 18. | Uncharacterized protein C6orf118; Chromosome 6 open reading frame 118. | 0.630 |
PRR18 | SFT2D1 | ENSP00000319590 | ENSP00000354590 | Proline-rich protein 18; Proline rich 18. | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | 0.651 |
RPS6KA2 | SFT2D1 | ENSP00000422435 | ENSP00000354590 | Ribosomal protein S6 kinase alpha-2; Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells. | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | 0.554 |
SFT2D1 | C6orf118 | ENSP00000354590 | ENSP00000230301 | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | Uncharacterized protein C6orf118; Chromosome 6 open reading frame 118. | 0.593 |
SFT2D1 | CTDNEP1 | ENSP00000354590 | ENSP00000460683 | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | CTD nuclear envelope phosphatase 1; Serine/threonine protein phosphatase forming with CNEP1R1 an active phosphatase complex that dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at different levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and [...] | 0.497 |
SFT2D1 | FAM43A | ENSP00000354590 | ENSP00000371397 | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | Protein FAM43A; Family with sequence similarity 43 member A; Belongs to the FAM43 family. | 0.496 |
SFT2D1 | GOLT1A | ENSP00000354590 | ENSP00000308535 | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | Vesicle transport protein GOT1A; May be involved in fusion of ER-derived transport vesicles with the Golgi complex; Belongs to the GOT1 family. | 0.519 |
SFT2D1 | MAL2 | ENSP00000354590 | ENSP00000479708 | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | Protein MAL2; Member of the machinery of polarized transport. Required for the indirect transcytotic route at the step of the egress of the transcytosing cargo from perinuclear endosomes in order for it to travel to the apical surface via a raft-dependent pathway. | 0.446 |
SFT2D1 | PRR18 | ENSP00000354590 | ENSP00000319590 | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | Proline-rich protein 18; Proline rich 18. | 0.651 |
SFT2D1 | RPS6KA2 | ENSP00000354590 | ENSP00000422435 | Vesicle transport protein SFT2A; May be involved in fusion of retrograde transport vesicles derived from an endocytic compartment with the Golgi complex. Belongs to the SFT2 family. | Ribosomal protein S6 kinase alpha-2; Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells. | 0.554 |