node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GAD1 | GAD2 | ENSP00000350928 | ENSP00000365437 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Glutamate decarboxylase 2; Catalyzes the production of GABA. | 0.968 |
GAD1 | GPHN | ENSP00000350928 | ENSP00000417901 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Molybdopterin molybdenumtransferase; Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. In the C-terminal section; belongs to the MoeA family. | 0.660 |
GAD1 | SLC17A6 | ENSP00000350928 | ENSP00000263160 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. | 0.884 |
GAD1 | SLC17A7 | ENSP00000350928 | ENSP00000221485 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Vesicular glutamate transporter 1; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. | 0.852 |
GAD1 | SLC17A8 | ENSP00000350928 | ENSP00000316909 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Vesicular glutamate transporter 3; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. | 0.628 |
GAD1 | SLC18A2 | ENSP00000350928 | ENSP00000496339 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Synaptic vesicular amine transporter; Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis. | 0.526 |
GAD1 | SLC18A3 | ENSP00000350928 | ENSP00000363229 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Vesicular acetylcholine transporter; Involved in acetylcholine transport into synaptic vesicles. | 0.655 |
GAD1 | SLC32A1 | ENSP00000350928 | ENSP00000217420 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles. | 0.977 |
GAD1 | SYT1 | ENSP00000350928 | ENSP00000261205 | Glutamate decarboxylase 1; Catalyzes the production of GABA. | Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)- dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-in [...] | 0.748 |
GAD2 | GAD1 | ENSP00000365437 | ENSP00000350928 | Glutamate decarboxylase 2; Catalyzes the production of GABA. | Glutamate decarboxylase 1; Catalyzes the production of GABA. | 0.968 |
GAD2 | GPHN | ENSP00000365437 | ENSP00000417901 | Glutamate decarboxylase 2; Catalyzes the production of GABA. | Molybdopterin molybdenumtransferase; Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. In the C-terminal section; belongs to the MoeA family. | 0.716 |
GAD2 | SLC17A6 | ENSP00000365437 | ENSP00000263160 | Glutamate decarboxylase 2; Catalyzes the production of GABA. | Vesicular glutamate transporter 2; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily. | 0.844 |
GAD2 | SLC17A7 | ENSP00000365437 | ENSP00000221485 | Glutamate decarboxylase 2; Catalyzes the production of GABA. | Vesicular glutamate transporter 1; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. | 0.883 |
GAD2 | SLC17A8 | ENSP00000365437 | ENSP00000316909 | Glutamate decarboxylase 2; Catalyzes the production of GABA. | Vesicular glutamate transporter 3; Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. May also mediate the transport of inorganic phosphate. | 0.610 |
GAD2 | SLC18A2 | ENSP00000365437 | ENSP00000496339 | Glutamate decarboxylase 2; Catalyzes the production of GABA. | Synaptic vesicular amine transporter; Involved in the ATP-dependent vesicular transport of biogenic amine neurotransmitters. Pumps cytosolic monoamines including dopamine, norepinephrine, serotonin, and histamine into synaptic vesicles. Requisite for vesicular amine storage prior to secretion via exocytosis. | 0.468 |
GAD2 | SLC18A3 | ENSP00000365437 | ENSP00000363229 | Glutamate decarboxylase 2; Catalyzes the production of GABA. | Vesicular acetylcholine transporter; Involved in acetylcholine transport into synaptic vesicles. | 0.605 |
GAD2 | SLC32A1 | ENSP00000365437 | ENSP00000217420 | Glutamate decarboxylase 2; Catalyzes the production of GABA. | Vesicular inhibitory amino acid transporter; Involved in the uptake of GABA and glycine into the synaptic vesicles. | 0.987 |
GAD2 | SYT1 | ENSP00000365437 | ENSP00000261205 | Glutamate decarboxylase 2; Catalyzes the production of GABA. | Synaptotagmin-1; Calcium sensor that participates in triggering neurotransmitter release at the synapse (By similarity). May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity). It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca(2+)- dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca(2+)-in [...] | 0.872 |
GPHN | GAD1 | ENSP00000417901 | ENSP00000350928 | Molybdopterin molybdenumtransferase; Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. In the C-terminal section; belongs to the MoeA family. | Glutamate decarboxylase 1; Catalyzes the production of GABA. | 0.660 |
GPHN | GAD2 | ENSP00000417901 | ENSP00000365437 | Molybdopterin molybdenumtransferase; Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. In the C-terminal section; belongs to the MoeA family. | Glutamate decarboxylase 2; Catalyzes the production of GABA. | 0.716 |