STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPATA24Spermatogenesis-associated protein 24; Binds DNA with high affinity but does not bind to TATA boxes. Synergises with GMNN and TBP in activation of TATA box-containing promoters and with GMNN and TBPL1 in activation of the NF1 TATA-less promoter. May play a role in cytoplasm movement and removal during spermiogenesis (By similarity). (205 aa)    
Predicted Functional Partners:
DNAJC18
DnaJ heat shock protein family member C18.
      
 0.672
SMIM33
Small integral membrane protein 33.
      
 0.664
LRCOL1
Leucine-rich colipase-like protein 1; Leucine rich colipase like 1.
      
 0.581
PROB1
Proline rich basic protein 1.
   
  
 0.561
FAM229B
Protein FAM229B; Family with sequence similarity 229 member B; Belongs to the FAM229 family.
   
  
 0.554
ZSCAN2
Zinc finger and SCAN domain-containing protein 2; May be involved in transcriptional regulation during the post-meiotic stages of spermatogenesis.
      
 0.541
FAM13B
Protein FAM13B; Family with sequence similarity 13 member B.
      
 0.513
SPATA21
Spermatogenesis-associated protein 21; Involved in the differentiation of haploid spermatids.
      
 0.503
CTNNBIP1
Beta-catenin-interacting protein 1; Prevents the interaction between CTNNB1 and TCF family members, and acts as negative regulator of the Wnt signaling pathway. Belongs to the CTNNBIP1 family.
    
   0.502
SPATA3
Spermatogenesis-associated protein 3; Spermatogenesis associated 3.
      
 0.502
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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