STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPNS3Protein spinster homolog 3; Sphingolipid transporter (512 aa)    
Predicted Functional Partners:
SLC22A1
Solute carrier family 22 member 1; Translocates a broad array of organic cations with various structures and molecular weights including the model compounds 1-methyl-4-phenylpyridinium (MPP), tetraethylammonium (TEA), N-1-methylnicotinamide (NMN), 4-(4-(dimethylamino)styryl)- N-methylpyridinium (ASP), the endogenous compounds choline, guanidine, histamine, epinephrine, adrenaline, noradrenaline and dopamine, and the drugs quinine, and metformin. The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor [...]
    
 
 0.907
SVOPL
Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily
   
  
 0.599
SVOP
Synaptic vesicle 2-related protein; SV2 related protein
   
 
 0.599
TMEM180
Transmembrane protein 180
      
 0.579
ZNF319
Zinc finger protein 319; May be involved in transcriptional regulation; Zinc fingers C2H2-type
   
 
 0.574
MFSD9
Major facilitator superfamily domain containing 9
   
  
 0.567
MFSD8
Major facilitator superfamily domain-containing protein 8; May be a carrier that transport small solutes by using chemiosmotic ion gradients; Belongs to the major facilitator superfamily
   
  
 0.559
MFSD6L
Major facilitator superfamily domain containing 6 like
   
  
 0.555
MFSD11
UNC93-like protein MFSD11; Major facilitator superfamily domain containing 11; Belongs to the unc-93 family
   
  
 0.551
MFSD6
Major facilitator superfamily domain containing 6
      
 0.539
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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