node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
H3C13 | H3C14 | ENSP00000333277 | ENSP00000358154 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | H3 clustered histone 14. | 0.931 |
H3C13 | H3C15 | ENSP00000333277 | ENSP00000385479 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | H3 clustered histone 15. | 0.931 |
H3C13 | H4C11 | ENSP00000333277 | ENSP00000347168 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | H4 clustered histone 11. | 0.951 |
H3C13 | H4C12 | ENSP00000333277 | ENSP00000479794 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | H4 clustered histone 12. | 0.943 |
H3C13 | H4C2 | ENSP00000333277 | ENSP00000366974 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | H4 clustered histone 2. | 0.955 |
H3C13 | H4C3 | ENSP00000333277 | ENSP00000367034 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | H4 clustered histone 3. | 0.946 |
H3C13 | H4C6 | ENSP00000333277 | ENSP00000244537 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.999 |
H3C13 | H4C8 | ENSP00000333277 | ENSP00000489236 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | H4 clustered histone 8. | 0.946 |
H3C13 | H4C9 | ENSP00000333277 | ENSP00000481486 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | H4 clustered histone 9. | 0.946 |
H3C13 | SPTY2D1 | ENSP00000333277 | ENSP00000337991 | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | Protein SPT2 homolog; Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin. Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription. Binds DNA and histones and promotes nucleosome assembly (in vitro). Facilitates formation of tetrameric histone complexes containing histone H3 and H4. Modulates RNA polymerase 1-mediated transcription (By similarity). Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holli [...] | 0.911 |
H3C14 | H3C13 | ENSP00000358154 | ENSP00000333277 | H3 clustered histone 14. | Histone H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.931 |
H3C14 | H3C15 | ENSP00000358154 | ENSP00000385479 | H3 clustered histone 14. | H3 clustered histone 15. | 0.981 |
H3C14 | H4C11 | ENSP00000358154 | ENSP00000347168 | H3 clustered histone 14. | H4 clustered histone 11. | 0.965 |
H3C14 | H4C12 | ENSP00000358154 | ENSP00000479794 | H3 clustered histone 14. | H4 clustered histone 12. | 0.961 |
H3C14 | H4C2 | ENSP00000358154 | ENSP00000366974 | H3 clustered histone 14. | H4 clustered histone 2. | 0.969 |
H3C14 | H4C3 | ENSP00000358154 | ENSP00000367034 | H3 clustered histone 14. | H4 clustered histone 3. | 0.961 |
H3C14 | H4C6 | ENSP00000358154 | ENSP00000244537 | H3 clustered histone 14. | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. | 0.979 |
H3C14 | H4C8 | ENSP00000358154 | ENSP00000489236 | H3 clustered histone 14. | H4 clustered histone 8. | 0.964 |
H3C14 | H4C9 | ENSP00000358154 | ENSP00000481486 | H3 clustered histone 14. | H4 clustered histone 9. | 0.964 |
H3C14 | SPTY2D1 | ENSP00000358154 | ENSP00000337991 | H3 clustered histone 14. | Protein SPT2 homolog; Histone chaperone that stabilizes pre-existing histone tetramers and regulates replication-independent histone exchange on chromatin. Required for normal chromatin refolding in the coding region of transcribed genes, and for the suppression of spurious transcription. Binds DNA and histones and promotes nucleosome assembly (in vitro). Facilitates formation of tetrameric histone complexes containing histone H3 and H4. Modulates RNA polymerase 1-mediated transcription (By similarity). Binds DNA, with a preference for branched DNA species, such as Y-form DNA and Holli [...] | 0.909 |