node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CSAG1 | MAGEA1 | ENSP00000359310 | ENSP00000349085 | Putative chondrosarcoma-associated gene 1 protein; Chondrosarcoma associated gene 1. | Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. | 0.820 |
CSAG1 | SSX2 | ENSP00000359310 | ENSP00000338796 | Putative chondrosarcoma-associated gene 1 protein; Chondrosarcoma associated gene 1. | SSX family member 2. | 0.798 |
CTAG1B | MAGEA1 | ENSP00000332602 | ENSP00000349085 | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. | Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. | 0.910 |
CTAG1B | SSX1 | ENSP00000332602 | ENSP00000366118 | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. | Protein SSX1; Could act as a modulator of transcription; Belongs to the SSX family. | 0.667 |
CTAG1B | SSX2 | ENSP00000332602 | ENSP00000338796 | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. | SSX family member 2. | 0.814 |
CTAG1B | SSX2B | ENSP00000332602 | ENSP00000477922 | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. | SSX family member 2B. | 0.772 |
MAGEA1 | CSAG1 | ENSP00000349085 | ENSP00000359310 | Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. | Putative chondrosarcoma-associated gene 1 protein; Chondrosarcoma associated gene 1. | 0.820 |
MAGEA1 | CTAG1B | ENSP00000349085 | ENSP00000332602 | Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. | 0.910 |
MAGEA1 | SSX1 | ENSP00000349085 | ENSP00000366118 | Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. | Protein SSX1; Could act as a modulator of transcription; Belongs to the SSX family. | 0.726 |
MAGEA1 | SSX2 | ENSP00000349085 | ENSP00000338796 | Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. | SSX family member 2. | 0.816 |
MAGEA1 | SSX2B | ENSP00000349085 | ENSP00000477922 | Melanoma-associated antigen 1; May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes. | SSX family member 2B. | 0.679 |
SMARCA2 | SS18 | ENSP00000371638 | ENSP00000414516 | Probable global transcription activator SNF2L2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural develop [...] | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | 0.996 |
SMARCA2 | SSX2 | ENSP00000371638 | ENSP00000338796 | Probable global transcription activator SNF2L2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural develop [...] | SSX family member 2. | 0.808 |
SS18 | SMARCA2 | ENSP00000414516 | ENSP00000371638 | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | Probable global transcription activator SNF2L2; Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Binds DNA non-specifically. Belongs to the neural progenitors-specific chromatin remodeling complex (npBAF complex) and the neuron-specific chromatin remodeling complex (nBAF complex). During neural develop [...] | 0.996 |
SS18 | SSX1 | ENSP00000414516 | ENSP00000366118 | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | Protein SSX1; Could act as a modulator of transcription; Belongs to the SSX family. | 0.969 |
SS18 | SSX2 | ENSP00000414516 | ENSP00000338796 | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | SSX family member 2. | 0.986 |
SS18 | SSX2B | ENSP00000414516 | ENSP00000477922 | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | SSX family member 2B. | 0.918 |
SS18 | SSX3 | ENSP00000414516 | ENSP00000298396 | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | Protein SSX3; Could act as a modulator of transcription; Belongs to the SSX family. | 0.718 |
SS18 | TLE1 | ENSP00000414516 | ENSP00000365682 | Protein SSXT; Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation. Component of SWI/SNF chromatin remodeling subcomplex GBAF that carries out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. | Transducin-like enhancer protein 1; Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full- length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG. Belongs to the WD repeat Groucho/TLE family. | 0.838 |
SSX1 | CTAG1B | ENSP00000366118 | ENSP00000332602 | Protein SSX1; Could act as a modulator of transcription; Belongs to the SSX family. | Cancer/testis antigen 1B; Belongs to the CTAG/PCC1 family. | 0.667 |