node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
C11orf49 | LRRC49 | ENSP00000367878 | ENSP00000453273 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | 0.906 |
C11orf49 | NICN1 | ENSP00000367878 | ENSP00000273598 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Nicolin-1; Nicolin 1. | 0.818 |
C11orf49 | TBC1D19 | ENSP00000367878 | ENSP00000264866 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | TBC1 domain family member 19; May act as a GTPase-activating protein for Rab family protein(s). | 0.647 |
C11orf49 | TPGS1 | ENSP00000367878 | ENSP00000352265 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.753 |
C11orf49 | TTLL1 | ENSP00000367878 | ENSP00000266254 | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity). | 0.872 |
C20orf194 | TBC1D19 | ENSP00000252032 | ENSP00000264866 | Uncharacterized protein C20orf194; May act as an effector for ARL3. | TBC1 domain family member 19; May act as a GTPase-activating protein for Rab family protein(s). | 0.616 |
LRRC49 | C11orf49 | ENSP00000453273 | ENSP00000367878 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | 0.906 |
LRRC49 | NICN1 | ENSP00000453273 | ENSP00000273598 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | Nicolin-1; Nicolin 1. | 0.981 |
LRRC49 | TBC1D19 | ENSP00000453273 | ENSP00000264866 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | TBC1 domain family member 19; May act as a GTPase-activating protein for Rab family protein(s). | 0.803 |
LRRC49 | TPGS1 | ENSP00000453273 | ENSP00000352265 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.987 |
LRRC49 | TTLL1 | ENSP00000453273 | ENSP00000266254 | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity). | 0.985 |
NICN1 | C11orf49 | ENSP00000273598 | ENSP00000367878 | Nicolin-1; Nicolin 1. | UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family. | 0.818 |
NICN1 | LRRC49 | ENSP00000273598 | ENSP00000453273 | Nicolin-1; Nicolin 1. | Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49. | 0.981 |
NICN1 | TBC1D19 | ENSP00000273598 | ENSP00000264866 | Nicolin-1; Nicolin 1. | TBC1 domain family member 19; May act as a GTPase-activating protein for Rab family protein(s). | 0.826 |
NICN1 | TPGS1 | ENSP00000273598 | ENSP00000352265 | Nicolin-1; Nicolin 1. | Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity). | 0.971 |
NICN1 | TTLL1 | ENSP00000273598 | ENSP00000266254 | Nicolin-1; Nicolin 1. | Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity). | 0.977 |
TBC1D10C | TBC1D13 | ENSP00000443654 | ENSP00000361731 | Carabin; Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras. | TBC1 domain family member 13; Acts as a GTPase-activating protein for RAB35. Together with RAB35 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes. | 0.620 |
TBC1D10C | TBC1D19 | ENSP00000443654 | ENSP00000264866 | Carabin; Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras. | TBC1 domain family member 19; May act as a GTPase-activating protein for Rab family protein(s). | 0.591 |
TBC1D10C | TBC1D21 | ENSP00000443654 | ENSP00000300504 | Carabin; Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras. | TBC1 domain family member 21; May act as a GTPase-activating protein for Rab family protein(s). May be involved in acrosome formation and cytoskeletal reorganization during spermiogenesis, possibly by regulating RAB3A activity. | 0.593 |
TBC1D13 | TBC1D10C | ENSP00000361731 | ENSP00000443654 | TBC1 domain family member 13; Acts as a GTPase-activating protein for RAB35. Together with RAB35 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes. | Carabin; Inhibits the Ras signaling pathway through its intrinsic Ras GTPase-activating protein (GAP) activity. Acts as a negative feedback inhibitor of the calcineurin signaling pathway that also mediates crosstalk between calcineurin and Ras. | 0.620 |