node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CEACAM16 | GJB2 | ENSP00000466561 | ENSP00000372295 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | Gap junction beta-2 protein; Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. | 0.420 |
CEACAM16 | OTOA | ENSP00000466561 | ENSP00000496564 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family. | 0.509 |
CEACAM16 | STRC | ENSP00000466561 | ENSP00000401513 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | Stereocilin; Essential to the formation of horizontal top connectors between outer hair cell stereocilia; Belongs to the stereocilin family. | 0.655 |
CEACAM16 | TECTA | ENSP00000466561 | ENSP00000376543 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.904 |
CEACAM16 | TECTB | ENSP00000466561 | ENSP00000494896 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | Beta-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.857 |
COCH | FAU | ENSP00000216361 | ENSP00000431822 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | 0.830 |
COCH | GJB2 | ENSP00000216361 | ENSP00000372295 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Gap junction beta-2 protein; Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. | 0.457 |
COCH | OTOA | ENSP00000216361 | ENSP00000496564 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family. | 0.511 |
COCH | OTOS | ENSP00000216361 | ENSP00000375849 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Otospiralin; May be essential for the survival of the neurosensory epithelium of the inner ear. | 0.479 |
COCH | STRC | ENSP00000216361 | ENSP00000401513 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Stereocilin; Essential to the formation of horizontal top connectors between outer hair cell stereocilia; Belongs to the stereocilin family. | 0.421 |
COCH | TECTA | ENSP00000216361 | ENSP00000376543 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.782 |
COCH | TECTB | ENSP00000216361 | ENSP00000494896 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Beta-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.902 |
FAU | COCH | ENSP00000431822 | ENSP00000216361 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | 0.830 |
FAU | MUC2 | ENSP00000431822 | ENSP00000494061 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Mucin-2; Coats the epithelia of the intestines, airways, and other mucus membrane-containing organs. Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces. Major constituent of both the inner and outer mucus layers of the colon and may play a role in excluding bacteria from the inner mucus layer. | 0.806 |
FAU | TECTA | ENSP00000431822 | ENSP00000376543 | Ubiquitin-like protein FUBI; FAU ubiquitin like and ribosomal protein S30 fusion. | Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.867 |
GJB2 | CEACAM16 | ENSP00000372295 | ENSP00000466561 | Gap junction beta-2 protein; Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | 0.420 |
GJB2 | COCH | ENSP00000372295 | ENSP00000216361 | Gap junction beta-2 protein; Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | 0.457 |
GJB2 | OTOA | ENSP00000372295 | ENSP00000496564 | Gap junction beta-2 protein; Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. | Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family. | 0.620 |
GJB2 | STRC | ENSP00000372295 | ENSP00000401513 | Gap junction beta-2 protein; Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. | Stereocilin; Essential to the formation of horizontal top connectors between outer hair cell stereocilia; Belongs to the stereocilin family. | 0.720 |
GJB2 | TECTA | ENSP00000372295 | ENSP00000376543 | Gap junction beta-2 protein; Structural component of gap junctions. Gap junctions are dodecameric channels that connect the cytoplasm of adjoining cells. They are formed by the docking of two hexameric hemichannels, one from each cell membrane. Small molecules and ions diffuse from one cell to a neighboring cell via the central pore. | Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.643 |