node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CALB1 | COCH | ENSP00000265431 | ENSP00000216361 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | 0.675 |
CALB1 | TECTB | ENSP00000265431 | ENSP00000494896 | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | Beta-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.666 |
CEACAM16 | OTOA | ENSP00000466561 | ENSP00000496564 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family. | 0.509 |
CEACAM16 | OTOG | ENSP00000466561 | ENSP00000382323 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | Otogelin; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity). | 0.757 |
CEACAM16 | OTOGL | ENSP00000466561 | ENSP00000447211 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | Otogelin-like protein; Otogelin like. | 0.747 |
CEACAM16 | TECTA | ENSP00000466561 | ENSP00000376543 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.904 |
CEACAM16 | TECTB | ENSP00000466561 | ENSP00000494896 | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | Beta-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.857 |
COCH | CALB1 | ENSP00000216361 | ENSP00000265431 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Calbindin; Buffers cytosolic calcium. May stimulate a membrane Ca(2+)- ATPase and a 3',5'-cyclic nucleotide phosphodiesterase. | 0.675 |
COCH | OTOA | ENSP00000216361 | ENSP00000496564 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family. | 0.511 |
COCH | OTOG | ENSP00000216361 | ENSP00000382323 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Otogelin; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity). | 0.429 |
COCH | TECTA | ENSP00000216361 | ENSP00000376543 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.782 |
COCH | TECTB | ENSP00000216361 | ENSP00000494896 | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | Beta-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.902 |
NID1 | TECTA | ENSP00000264187 | ENSP00000376543 | Nidogen-1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions. | Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.442 |
NID1 | TECTB | ENSP00000264187 | ENSP00000494896 | Nidogen-1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions. | Beta-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.742 |
NID1 | ZAN | ENSP00000264187 | ENSP00000480750 | Nidogen-1; Sulfated glycoprotein widely distributed in basement membranes and tightly associated with laminin. Also binds to collagen IV and perlecan. It probably has a role in cell-extracellular matrix interactions. | Zonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling. | 0.844 |
OTOA | CEACAM16 | ENSP00000496564 | ENSP00000466561 | Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family. | Carcinoembryonic antigen-related cell adhesion molecule 16; Required for proper hearing, plays a role in maintaining the integrity of the tectorial membrane. | 0.509 |
OTOA | COCH | ENSP00000496564 | ENSP00000216361 | Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family. | Cochlin; Plays a role in the control of cell shape and motility in the trabecular meshwork. | 0.511 |
OTOA | OTOG | ENSP00000496564 | ENSP00000382323 | Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family. | Otogelin; Glycoprotein specific to acellular membranes of the inner ear. May be required for the anchoring of the otoconial membranes and cupulae to the underlying neuroepithelia in the vestibule. May be involved in the organization and/or stabilization of the fibrillar network that compose the tectorial membrane in the cochlea. May play a role in mechanotransduction processes (By similarity). | 0.955 |
OTOA | TECTA | ENSP00000496564 | ENSP00000376543 | Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family. | Alpha-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.930 |
OTOA | TECTB | ENSP00000496564 | ENSP00000494896 | Otoancorin; May act as an adhesion molecule; Belongs to the stereocilin family. | Beta-tectorin; One of the major non-collagenous components of the tectorial membrane (By similarity). The tectorial membrane is an extracellular matrix of the inner ear that covers the neuroepithelium of the cochlea and contacts the stereocilia bundles of specialized sensory hair cells. Sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia and leads to fluctuations in hair- cell membrane potential, transducing sound into electrical signals. | 0.925 |