node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
COQ3 | TGDS | ENSP00000254759 | ENSP00000261296 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway. | TDP-glucose 4,6-dehydratase. | 0.845 |
EIF2B3 | EIF2B5 | ENSP00000353575 | ENSP00000497160 | Translation initiation factor eIF-2B subunit gamma; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. | Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. | 0.999 |
EIF2B3 | TGDS | ENSP00000353575 | ENSP00000261296 | Translation initiation factor eIF-2B subunit gamma; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. | TDP-glucose 4,6-dehydratase. | 0.818 |
EIF2B3 | UGDH | ENSP00000353575 | ENSP00000319501 | Translation initiation factor eIF-2B subunit gamma; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. | UDP-glucose 6-dehydrogenase; Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.441 |
EIF2B5 | EIF2B3 | ENSP00000497160 | ENSP00000353575 | Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. | Translation initiation factor eIF-2B subunit gamma; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. | 0.999 |
EIF2B5 | TGDS | ENSP00000497160 | ENSP00000261296 | Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. | TDP-glucose 4,6-dehydratase. | 0.816 |
EIF2B5 | UGDH | ENSP00000497160 | ENSP00000319501 | Translation initiation factor eIF-2B subunit epsilon; Catalyzes the exchange of eukaryotic initiation factor 2- bound GDP for GTP; Belongs to the eIF-2B gamma/epsilon subunits family. | UDP-glucose 6-dehydrogenase; Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.438 |
G3V4G9_HUMAN | TGDS | ENSP00000451792 | ENSP00000261296 | Ig-like domain-containing protein. | TDP-glucose 4,6-dehydratase. | 0.778 |
GALT | GMPPA | ENSP00000368119 | ENSP00000350949 | Galactose-1-phosphate uridylyltransferase; Plays an important role in galactose metabolism. | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | 0.506 |
GALT | GMPPB | ENSP00000368119 | ENSP00000309092 | Galactose-1-phosphate uridylyltransferase; Plays an important role in galactose metabolism. | Mannose-1-phosphate guanyltransferase beta; Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids. Belongs to the transferase hexapeptide repeat family. | 0.459 |
GALT | IL11RA | ENSP00000368119 | ENSP00000450565 | Galactose-1-phosphate uridylyltransferase; Plays an important role in galactose metabolism. | Interleukin-11 receptor subunit alpha; Receptor for interleukin-11. The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells. Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number. | 0.930 |
GALT | TGDS | ENSP00000368119 | ENSP00000261296 | Galactose-1-phosphate uridylyltransferase; Plays an important role in galactose metabolism. | TDP-glucose 4,6-dehydratase. | 0.780 |
GALT | UGDH | ENSP00000368119 | ENSP00000319501 | Galactose-1-phosphate uridylyltransferase; Plays an important role in galactose metabolism. | UDP-glucose 6-dehydrogenase; Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.878 |
GMPPA | GALT | ENSP00000350949 | ENSP00000368119 | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | Galactose-1-phosphate uridylyltransferase; Plays an important role in galactose metabolism. | 0.506 |
GMPPA | GMPPB | ENSP00000350949 | ENSP00000309092 | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | Mannose-1-phosphate guanyltransferase beta; Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids. Belongs to the transferase hexapeptide repeat family. | 0.999 |
GMPPA | TGDS | ENSP00000350949 | ENSP00000261296 | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | TDP-glucose 4,6-dehydratase. | 0.818 |
GMPPA | UGDH | ENSP00000350949 | ENSP00000319501 | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | UDP-glucose 6-dehydrogenase; Catalyzes the formation of UDP-alpha-D-glucuronate, a constituent of complex glycosaminoglycans. Required for the biosynthesis of chondroitin sulfate and heparan sulfate. Required for embryonic development via its role in the biosynthesis of glycosaminoglycans (By similarity). Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. | 0.565 |
GMPPB | GALT | ENSP00000309092 | ENSP00000368119 | Mannose-1-phosphate guanyltransferase beta; Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids. Belongs to the transferase hexapeptide repeat family. | Galactose-1-phosphate uridylyltransferase; Plays an important role in galactose metabolism. | 0.459 |
GMPPB | GMPPA | ENSP00000309092 | ENSP00000350949 | Mannose-1-phosphate guanyltransferase beta; Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids. Belongs to the transferase hexapeptide repeat family. | Mannose-1-phosphate guanyltransferase alpha; May serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. | 0.999 |
GMPPB | TGDS | ENSP00000309092 | ENSP00000261296 | Mannose-1-phosphate guanyltransferase beta; Catalyzes the formation of GDP-mannose, an essential precursor of glycan moieties of glycoproteins and glycolipids. Belongs to the transferase hexapeptide repeat family. | TDP-glucose 4,6-dehydratase. | 0.845 |