STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TIGD2Tigger transposable element derived 2. (525 aa)    
Predicted Functional Partners:
HARBI1
Putative nuclease HARBI1; Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.
   
  
 0.521
GPRIN3
G protein-regulated inducer of neurite outgrowth 3; May be involved in neurite outgrowth.
   
  
 0.488
POGK
Pogo transposable element derived with KRAB domain.
   
  
 0.477
NAIF1
Nuclear apoptosis-inducing factor 1; Induces apoptosis; Belongs to the NAIF1 family.
   
  
 0.458
SMIM13
Small integral membrane protein 13.
   
  
 0.453
C19orf47
Uncharacterized protein C19orf47; Chromosome 19 open reading frame 47.
   
  
 0.437
C19orf54
UPF0692 protein C19orf54; Chromosome 19 open reading frame 54.
      
 0.418
CCSER1
Coiled-coil serine rich protein 1.
   
  
 0.417
UBE2I
SUMO-conjugating enzyme UBC9; Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3, SUMO4 and SUMO1P1/SUMO5 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2, CBX4 and ZNF451. Can catalyze the formation of poly-SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Sumoylates p53/TP53 at 'Lys-386'. Mediates sumoylation of ERCC6 which is essential for its transcription-coupled nucleotide excision repair activity. Belongs to the ubiqu [...]
    
   0.416
PYURF
Protein preY, mitochondrial; PIGY upstream reading frame; Belongs to the PREY family.
      
 0.405
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.