node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANTKMT | TMEM104 | ENSP00000454380 | ENSP00000334849 | Adenine nucleotide translocase lysine N-methyltransferase; Mitochondrial protein-lysine N-methyltransferase that trimethylates adenine nucleotide translocases ANT2/SLC25A5 and ANT3/SLC25A6, thereby regulating mitochondrial respiration. Probably also trimethylates ANT1/SLC25A4. | Transmembrane protein 104; Belongs to the TMEM104 family. | 0.566 |
FDXR | TMEM104 | ENSP00000416515 | ENSP00000334849 | NADPH:adrenodoxin oxidoreductase, mitochondrial; Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C- 27 hydroxylation in the liver. | Transmembrane protein 104; Belongs to the TMEM104 family. | 0.492 |
HTR3C | TMEM104 | ENSP00000322617 | ENSP00000334849 | 5-hydroxytryptamine receptor 3C; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand- gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. | Transmembrane protein 104; Belongs to the TMEM104 family. | 0.450 |
PSKH1 | TBC1D13 | ENSP00000291041 | ENSP00000361731 | Serine/threonine-protein kinase H1; May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing. | TBC1 domain family member 13; Acts as a GTPase-activating protein for RAB35. Together with RAB35 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes. | 0.426 |
PSKH1 | TMEM104 | ENSP00000291041 | ENSP00000334849 | Serine/threonine-protein kinase H1; May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing. | Transmembrane protein 104; Belongs to the TMEM104 family. | 0.446 |
SPNS3 | SVOP | ENSP00000347721 | ENSP00000479104 | Protein spinster homolog 3; Sphingolipid transporter. | Synaptic vesicle 2-related protein; SV2 related protein. | 0.523 |
SPNS3 | SVOPL | ENSP00000347721 | ENSP00000405482 | Protein spinster homolog 3; Sphingolipid transporter. | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily. | 0.586 |
SPNS3 | TMEM104 | ENSP00000347721 | ENSP00000334849 | Protein spinster homolog 3; Sphingolipid transporter. | Transmembrane protein 104; Belongs to the TMEM104 family. | 0.445 |
SPNS3 | UNC93A | ENSP00000347721 | ENSP00000230256 | Protein spinster homolog 3; Sphingolipid transporter. | Unc-93 homolog A. | 0.494 |
SVOP | SPNS3 | ENSP00000479104 | ENSP00000347721 | Synaptic vesicle 2-related protein; SV2 related protein. | Protein spinster homolog 3; Sphingolipid transporter. | 0.523 |
SVOP | TMEM104 | ENSP00000479104 | ENSP00000334849 | Synaptic vesicle 2-related protein; SV2 related protein. | Transmembrane protein 104; Belongs to the TMEM104 family. | 0.488 |
SVOP | UNC93A | ENSP00000479104 | ENSP00000230256 | Synaptic vesicle 2-related protein; SV2 related protein. | Unc-93 homolog A. | 0.620 |
SVOPL | SPNS3 | ENSP00000405482 | ENSP00000347721 | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily. | Protein spinster homolog 3; Sphingolipid transporter. | 0.586 |
SVOPL | TMEM104 | ENSP00000405482 | ENSP00000334849 | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily. | Transmembrane protein 104; Belongs to the TMEM104 family. | 0.470 |
SVOPL | UNC93A | ENSP00000405482 | ENSP00000230256 | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily. | Unc-93 homolog A. | 0.637 |
TBC1D13 | PSKH1 | ENSP00000361731 | ENSP00000291041 | TBC1 domain family member 13; Acts as a GTPase-activating protein for RAB35. Together with RAB35 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes. | Serine/threonine-protein kinase H1; May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing. | 0.426 |
TBC1D13 | TMEM104 | ENSP00000361731 | ENSP00000334849 | TBC1 domain family member 13; Acts as a GTPase-activating protein for RAB35. Together with RAB35 may be involved in regulation of insulin-induced glucose transporter SLC2A4/GLUT4 translocation to the plasma membrane in adipocytes. | Transmembrane protein 104; Belongs to the TMEM104 family. | 0.464 |
TMEM104 | ANTKMT | ENSP00000334849 | ENSP00000454380 | Transmembrane protein 104; Belongs to the TMEM104 family. | Adenine nucleotide translocase lysine N-methyltransferase; Mitochondrial protein-lysine N-methyltransferase that trimethylates adenine nucleotide translocases ANT2/SLC25A5 and ANT3/SLC25A6, thereby regulating mitochondrial respiration. Probably also trimethylates ANT1/SLC25A4. | 0.566 |
TMEM104 | FDXR | ENSP00000334849 | ENSP00000416515 | Transmembrane protein 104; Belongs to the TMEM104 family. | NADPH:adrenodoxin oxidoreductase, mitochondrial; Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C- 27 hydroxylation in the liver. | 0.492 |
TMEM104 | HTR3C | ENSP00000334849 | ENSP00000322617 | Transmembrane protein 104; Belongs to the TMEM104 family. | 5-hydroxytryptamine receptor 3C; This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand- gated ion channel, which when activated causes fast, depolarizing responses. It is a cation-specific, but otherwise relatively nonselective, ion channel. | 0.450 |