node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCDC169 | TMEM161B | ENSP00000426174 | ENSP00000426354 | Coiled-coil domain containing 169. | Transmembrane protein 161B; Belongs to the TMEM161 family. | 0.509 |
FUT10 | PIGG | ENSP00000332757 | ENSP00000415203 | Alpha-(1,3)-fucosyltransferase 10; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. | GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose. | 0.435 |
FUT10 | PSD3 | ENSP00000332757 | ENSP00000324127 | Alpha-(1,3)-fucosyltransferase 10; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. | PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6. | 0.402 |
FUT10 | TMEM161B | ENSP00000332757 | ENSP00000426354 | Alpha-(1,3)-fucosyltransferase 10; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. | Transmembrane protein 161B; Belongs to the TMEM161 family. | 0.478 |
KBTBD12 | TMEM117 | ENSP00000385957 | ENSP00000266534 | Kelch repeat and BTB domain containing 12. | Transmembrane protein 117; Involved in endoplasmic reticulum (ER) stress-induced cell death pathway; Belongs to the TMEM117 family. | 0.525 |
KBTBD12 | TMEM161B | ENSP00000385957 | ENSP00000426354 | Kelch repeat and BTB domain containing 12. | Transmembrane protein 161B; Belongs to the TMEM161 family. | 0.560 |
LHPP | OLFM4 | ENSP00000357835 | ENSP00000219022 | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase; Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity); Belongs to the HAD-like hydrolase superfamily. | Olfactomedin-4; May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. | 0.443 |
LHPP | TMEM161B | ENSP00000357835 | ENSP00000426354 | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase; Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity); Belongs to the HAD-like hydrolase superfamily. | Transmembrane protein 161B; Belongs to the TMEM161 family. | 0.651 |
MEF2C | TMEM161B | ENSP00000340874 | ENSP00000426354 | Myocyte-specific enhancer factor 2C; Transcription activator which binds specifically to the MEF2 element present in the regulatory regions of many muscle-specific genes. Controls cardiac morphogenesis and myogenesis, and is also involved in vascular development. Enhances transcriptional activation mediated by SOX18. Plays an essential role in hippocampal-dependent learning and memory by suppressing the number of excitatory synapses and thus regulating basal and evoked synaptic transmission. Crucial for normal neuronal development, distribution, and electrical activity in the neocortex [...] | Transmembrane protein 161B; Belongs to the TMEM161 family. | 0.620 |
MXRA7 | TMEM161B | ENSP00000465103 | ENSP00000426354 | Matrix-remodeling-associated protein 7; Matrix remodeling associated 7. | Transmembrane protein 161B; Belongs to the TMEM161 family. | 0.529 |
OLFM4 | LHPP | ENSP00000219022 | ENSP00000357835 | Olfactomedin-4; May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. | Phospholysine phosphohistidine inorganic pyrophosphate phosphatase; Phosphatase that hydrolyzes imidodiphosphate, 3- phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity); Belongs to the HAD-like hydrolase superfamily. | 0.443 |
OLFM4 | TMEM161B | ENSP00000219022 | ENSP00000426354 | Olfactomedin-4; May promote proliferation of pancreatic cancer cells by favoring the transition from the S to G2/M phase. In myeloid leukemic cell lines, inhibits cell growth and induces cell differentiation and apoptosis. May play a role in the inhibition of EIF4EBP1 phosphorylation/deactivation. Facilitates cell adhesion, most probably through interaction with cell surface lectins and cadherin. | Transmembrane protein 161B; Belongs to the TMEM161 family. | 0.497 |
PIGG | FUT10 | ENSP00000415203 | ENSP00000332757 | GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose. | Alpha-(1,3)-fucosyltransferase 10; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. | 0.435 |
PIGG | PSD3 | ENSP00000415203 | ENSP00000324127 | GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose. | PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6. | 0.476 |
PIGG | TMEM161B | ENSP00000415203 | ENSP00000426354 | GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose. | Transmembrane protein 161B; Belongs to the TMEM161 family. | 0.560 |
PSD3 | FUT10 | ENSP00000324127 | ENSP00000332757 | PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6. | Alpha-(1,3)-fucosyltransferase 10; Probable fucosyltransferase; Belongs to the glycosyltransferase 10 family. | 0.402 |
PSD3 | PIGG | ENSP00000324127 | ENSP00000415203 | PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6. | GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose. | 0.476 |
PSD3 | TMEM161B | ENSP00000324127 | ENSP00000426354 | PH and SEC7 domain-containing protein 3; Guanine nucleotide exchange factor for ARF6. | Transmembrane protein 161B; Belongs to the TMEM161 family. | 0.529 |
TMEM117 | KBTBD12 | ENSP00000266534 | ENSP00000385957 | Transmembrane protein 117; Involved in endoplasmic reticulum (ER) stress-induced cell death pathway; Belongs to the TMEM117 family. | Kelch repeat and BTB domain containing 12. | 0.525 |
TMEM117 | TMEM161B | ENSP00000266534 | ENSP00000426354 | Transmembrane protein 117; Involved in endoplasmic reticulum (ER) stress-induced cell death pathway; Belongs to the TMEM117 family. | Transmembrane protein 161B; Belongs to the TMEM161 family. | 0.509 |