STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM179Transmembrane protein 179; Belongs to the TMEM179 family. (233 aa)    
Predicted Functional Partners:
OR4F15
Olfactory receptor 4F15; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.570
TMEM88B
Transmembrane protein 88B.
   
  
 0.530
KIF26A
Kinesin-like protein KIF26A; Atypical kinesin that plays a key role in enteric neuron development. Acts by repressing a cell growth signaling pathway in the enteric nervous system development, possibly via its interaction with GRB2 that prevents GRB2-binding to SHC, thereby attenating the GDNF-Ret signaling. Binds to microtubules but lacks microtubule-based motility due to the absence of ATPase activity (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. KIF26 subfamily.
   
  
 0.506
TMEM151A
Transmembrane protein 151A.
   
  
 0.485
FAM131B
Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family.
   
  
 0.481
OR4F6
Olfactory receptor 4F6; Odorant receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.480
TMEM128
Transmembrane protein 128.
      
 0.479
COA8
Cytochrome c oxidase assembly factor 8; Required for cytochrome c complex (COX) IV assembly and function Protects COX assembly from oxidation-induced degradation, COX being the terminal component of the mitochondrial respiratory chain.
      
 0.479
FAM189A1
Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family.
   
  
 0.478
FAM81A
Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family.
   
  
 0.475
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.