Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CCDC115 | TMEM211 | ENSP00000259229 | ENSP00000385494 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis. | Transmembrane protein 211. | 0.483 |
| CCDC115 | ZNF33B | ENSP00000259229 | ENSP00000352444 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis. | Zinc finger protein 33B; May be involved in transcriptional regulation. | 0.407 |
| CCDC115 | ZNF418 | ENSP00000259229 | ENSP00000407039 | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis. | Zinc finger protein 418; Transcriptional repressor. | 0.488 |
| FAM166C | TMEM211 | ENSP00000332875 | ENSP00000385494 | Protein FAM166C; Family with sequence similarity 166 member C; Belongs to the FAM166C family. | Transmembrane protein 211. | 0.506 |
| GPR137C | OVOL3 | ENSP00000315106 | ENSP00000487603 | Integral membrane protein GPR137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes; Belongs to the GPR137 family. | Putative transcription factor ovo-like protein 3; May act as a transcription regulator; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.477 |
| GPR137C | TMEM211 | ENSP00000315106 | ENSP00000385494 | Integral membrane protein GPR137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes; Belongs to the GPR137 family. | Transmembrane protein 211. | 0.496 |
| GPR137C | TMEM221 | ENSP00000315106 | ENSP00000342162 | Integral membrane protein GPR137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes; Belongs to the GPR137 family. | Transmembrane protein 221. | 0.629 |
| GRAMD1C | SVOPL | ENSP00000350881 | ENSP00000405482 | Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol [...] | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily. | 0.455 |
| GRAMD1C | TMEM211 | ENSP00000350881 | ENSP00000385494 | Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol [...] | Transmembrane protein 211. | 0.504 |
| OVOL3 | GPR137C | ENSP00000487603 | ENSP00000315106 | Putative transcription factor ovo-like protein 3; May act as a transcription regulator; Belongs to the krueppel C2H2-type zinc-finger protein family. | Integral membrane protein GPR137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes; Belongs to the GPR137 family. | 0.477 |
| OVOL3 | TMEM211 | ENSP00000487603 | ENSP00000385494 | Putative transcription factor ovo-like protein 3; May act as a transcription regulator; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transmembrane protein 211. | 0.477 |
| OVOL3 | TMEM221 | ENSP00000487603 | ENSP00000342162 | Putative transcription factor ovo-like protein 3; May act as a transcription regulator; Belongs to the krueppel C2H2-type zinc-finger protein family. | Transmembrane protein 221. | 0.519 |
| SVOPL | GRAMD1C | ENSP00000405482 | ENSP00000350881 | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily. | Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol [...] | 0.455 |
| SVOPL | TMEM211 | ENSP00000405482 | ENSP00000385494 | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily. | Transmembrane protein 211. | 0.463 |
| TMEM211 | CCDC115 | ENSP00000385494 | ENSP00000259229 | Transmembrane protein 211. | Coiled-coil domain-containing protein 115; Accessory component of the proton-transporting vacuolar (V)- ATPase protein pump involved in intracellular iron homeostasis. In aerobic conditions, required for intracellular iron homeostasis, thus triggering the activity of Fe(2+) prolyl hydroxylase (PHD) enzymes, and leading to HIF1A hydroxylation and subsequent proteasomal degradation. Necessary for endolysosomal acidification and lysosomal degradation. May be involved in Golgi homeostasis. | 0.483 |
| TMEM211 | FAM166C | ENSP00000385494 | ENSP00000332875 | Transmembrane protein 211. | Protein FAM166C; Family with sequence similarity 166 member C; Belongs to the FAM166C family. | 0.506 |
| TMEM211 | GPR137C | ENSP00000385494 | ENSP00000315106 | Transmembrane protein 211. | Integral membrane protein GPR137C; Lysosomal integral membrane protein that may regulate MTORC1 complex translocation to lysosomes; Belongs to the GPR137 family. | 0.496 |
| TMEM211 | GRAMD1C | ENSP00000385494 | ENSP00000350881 | Transmembrane protein 211. | Protein Aster-C; Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol [...] | 0.504 |
| TMEM211 | OVOL3 | ENSP00000385494 | ENSP00000487603 | Transmembrane protein 211. | Putative transcription factor ovo-like protein 3; May act as a transcription regulator; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.477 |
| TMEM211 | SVOPL | ENSP00000385494 | ENSP00000405482 | Transmembrane protein 211. | Putative transporter SVOPL; SVOP like; Belongs to the major facilitator superfamily. | 0.463 |
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