STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM51Transmembrane protein 51. (253 aa)    
Predicted Functional Partners:
CCDC183
Coiled-coil domain containing 183.
      
 0.535
FRMPD1
FERM and PDZ domain-containing protein 1; Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1.
      
 0.502
LHFPL2
LHFPL tetraspan subfamily member 2 protein; Plays a role in female and male fertility. Involved in distal reproductive tract development.
   
  
 0.484
CCDC9B
Coiled-coil domain containing 9B.
   
  
 0.480
CDC42EP3
Cdc42 effector protein 3; Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.
      
 0.471
SPATS2L
SPATS2-like protein; Spermatogenesis associated serine rich 2 like; Belongs to the SPATS2 family.
   
  
 0.469
CPNE5
Copine-5; Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes (By similarity). Plays a role in dendrite formation by melanocytes ; Belongs to the copine family.
      
 0.468
MCTP2
Multiple C2 and transmembrane domain-containing protein 2; Might play a role in the development of cardiac outflow tract; Belongs to the MCTP family.
      
 0.457
TMEM86A
Lysoplasmalogenase-like protein TMEM86A; Transmembrane protein 86A.
   
  
 0.449
PTER
Phosphotriesterase-related protein; Phosphotriesterase related; Belongs to the metallo-dependent hydrolases superfamily. Phosphotriesterase family.
    
 
 0.449
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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