STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TMEM88BTransmembrane protein 88B. (163 aa)    
Predicted Functional Partners:
TMEM179
Transmembrane protein 179; Belongs to the TMEM179 family.
   
  
 0.530
TMEM145
Transmembrane protein 145.
   
  
 0.493
FAM189A1
Protein FAM189A1; Family with sequence similarity 189 member A1; Belongs to the FAM189 family.
   
  
 0.488
DZANK1
Double zinc ribbon and ankyrin repeat domains 1.
      
 0.470
FAM171B
Protein FAM171B; Family with sequence similarity 171 member B; Belongs to the FAM171 family.
   
  
 0.464
FAM81A
Protein FAM81A; Family with sequence similarity 81 member A; Belongs to the FAM81 family.
   
  
 0.460
FAM131B
Protein FAM131B; Family with sequence similarity 131 member B; Belongs to the FAM131 family.
   
  
 0.454
SH2D7
SH2 domain containing 7.
      
 0.447
TMEM59L
Transmembrane protein 59-like; Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding.
   
  
 0.445
TMPRSS5
Transmembrane protease serine 5; May play a role in hearing; Belongs to the peptidase S1 family.
   
  
 0.439
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
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