STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TPGS2Tubulin polyglutamylase complex subunit 2. (304 aa)    
Predicted Functional Partners:
TTLL1
Probable tubulin polyglutamylase TTLL1; Catalytic subunit of the neuronal tubulin polyglutamylase complex. Modifies alpha- and beta-tubulin, generating side chains of glutamate on the gamma-carboxyl groups of specific glutamate residues within the C-terminal tail of alpha- and beta-tubulin (By similarity).
   
 0.971
NICN1
Nicolin-1; Nicolin 1.
    
 0.971
LRRC49
Leucine-rich repeat-containing protein 49; Leucine rich repeat containing 49.
    
 0.971
TPGS1
Tubulin polyglutamylase complex subunit 1; May act in the targeting of the tubulin polyglutamylase complex. Required for the development of the spermatid flagellum (By similarity).
    
 0.949
C11orf49
UPF0705 protein C11orf49; Chromosome 11 open reading frame 49; Belongs to the UPF0705 family.
   
   0.854
KIAA1328
Protein hinderin; Competes with SMC1 for binding to SMC3. May affect the availability of SMC3 to engage in the formation of multimeric protein complexes.
   
  
 0.717
SAYSD1
SAYSVFN motif domain containing 1.
      
 0.584
C5orf22
UPF0489 protein C5orf22; Chromosome 5 open reading frame 22; Belongs to the UPF0489 family.
   
  
 0.574
TRMT13
tRNA:m(4)X modification enzyme TRM13 homolog; tRNA methylase which 2'-O-methylates cytidine(4) in tRNA(Pro) and tRNA(Gly)(GCC), and adenosine(4) in tRNA(His).
      
 0.549
PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis; Belongs to the PIGH family.
      
 0.501
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, human, man
Server load: low (32%) [HD]