node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CFAP206 | TTC23L | ENSP00000358575 | ENSP00000422188 | Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes. | Tetratricopeptide repeat domain 23 like. | 0.476 |
DTWD2 | EIPR1 | ENSP00000425048 | ENSP00000381652 | DTW domain containing 2. | EARP and GARP complex-interacting protein 1; Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein. Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome- associated recycling protein (EARP) complex. | 0.480 |
DTWD2 | TTC23L | ENSP00000425048 | ENSP00000422188 | DTW domain containing 2. | Tetratricopeptide repeat domain 23 like. | 0.484 |
EFCAB7 | IQCE | ENSP00000360129 | ENSP00000480715 | EF-hand calcium-binding domain-containing protein 7; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia. | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (By similarity). Required for proper limb morphogenesis. | 0.994 |
EFCAB7 | TTC23L | ENSP00000360129 | ENSP00000422188 | EF-hand calcium-binding domain-containing protein 7; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia. | Tetratricopeptide repeat domain 23 like. | 0.608 |
EIPR1 | DTWD2 | ENSP00000381652 | ENSP00000425048 | EARP and GARP complex-interacting protein 1; Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein. Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome- associated recycling protein (EARP) complex. | DTW domain containing 2. | 0.480 |
EIPR1 | TTC23L | ENSP00000381652 | ENSP00000422188 | EARP and GARP complex-interacting protein 1; Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein. Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome- associated recycling protein (EARP) complex. | Tetratricopeptide repeat domain 23 like. | 0.459 |
IQCE | EFCAB7 | ENSP00000480715 | ENSP00000360129 | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (By similarity). Required for proper limb morphogenesis. | EF-hand calcium-binding domain-containing protein 7; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia. | 0.994 |
IQCE | TTC23L | ENSP00000480715 | ENSP00000422188 | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (By similarity). Required for proper limb morphogenesis. | Tetratricopeptide repeat domain 23 like. | 0.761 |
MIA2 | TTC23L | ENSP00000491014 | ENSP00000422188 | Melanoma inhibitory activity protein 2; Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum. Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity). Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PR [...] | Tetratricopeptide repeat domain 23 like. | 0.514 |
RAI14 | TTC23L | ENSP00000427123 | ENSP00000422188 | Ankycorbin; Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood- testis barrier. | Tetratricopeptide repeat domain 23 like. | 0.559 |
SPINK14 | TTC23L | ENSP00000349459 | ENSP00000422188 | Serine protease inhibitor Kazal-type 14; May be a serine protease inhibitor. | Tetratricopeptide repeat domain 23 like. | 0.506 |
TTC23L | CFAP206 | ENSP00000422188 | ENSP00000358575 | Tetratricopeptide repeat domain 23 like. | Cilia- and flagella-associated protein 206; May regulate cilium motility through its role in the assembly of the axonemal radial spokes. | 0.476 |
TTC23L | DTWD2 | ENSP00000422188 | ENSP00000425048 | Tetratricopeptide repeat domain 23 like. | DTW domain containing 2. | 0.484 |
TTC23L | EFCAB7 | ENSP00000422188 | ENSP00000360129 | Tetratricopeptide repeat domain 23 like. | EF-hand calcium-binding domain-containing protein 7; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Required for the localization of the EVC2:EVC subcomplex at the base of primary cilia. | 0.608 |
TTC23L | EIPR1 | ENSP00000422188 | ENSP00000381652 | Tetratricopeptide repeat domain 23 like. | EARP and GARP complex-interacting protein 1; Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein. Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome- associated recycling protein (EARP) complex. | 0.459 |
TTC23L | IQCE | ENSP00000422188 | ENSP00000480715 | Tetratricopeptide repeat domain 23 like. | IQ domain-containing protein E; Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling (By similarity). Required for proper limb morphogenesis. | 0.761 |
TTC23L | MIA2 | ENSP00000422188 | ENSP00000491014 | Tetratricopeptide repeat domain 23 like. | Melanoma inhibitory activity protein 2; Plays a role in the transport of cargos that are too large to fit into COPII-coated vesicles and require specific mechanisms to be incorporated into membrane-bound carriers and exported from the endoplasmic reticulum. Plays a role in the secretion of lipoproteins, pre-chylomicrons and pre-VLDLs, by participating in their export from the endoplasmic reticulum. Thereby, may play a role in cholesterol and triglyceride homeostasis (By similarity). Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers and recruiting PR [...] | 0.514 |
TTC23L | RAI14 | ENSP00000422188 | ENSP00000427123 | Tetratricopeptide repeat domain 23 like. | Ankycorbin; Plays a role in actin regulation at the ectoplasmic specialization, a type of cell junction specific to testis. Important for establishment of sperm polarity and normal spermatid adhesion. May also promote integrity of Sertoli cell tight junctions at the blood- testis barrier. | 0.559 |
TTC23L | SPINK14 | ENSP00000422188 | ENSP00000349459 | Tetratricopeptide repeat domain 23 like. | Serine protease inhibitor Kazal-type 14; May be a serine protease inhibitor. | 0.506 |