Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATG2B | VPS13A | ENSP00000353010 | ENSP00000353422 | Autophagy-related protein 2 homolog B; Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion; Belongs to the ATG2 family. | Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane. | 0.527 |
| ATG2B | VPS13C | ENSP00000353010 | ENSP00000493560 | Autophagy-related protein 2 homolog B; Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion; Belongs to the ATG2 family. | Vacuolar protein sorting-associated protein 13C; Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential. Involved in the regulation of PINK1/PRKN-mediated mitophagy in response to mitochondrial depolarization. | 0.423 |
| ATG2B | VPS13D | ENSP00000353010 | ENSP00000478104 | Autophagy-related protein 2 homolog B; Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion; Belongs to the ATG2 family. | Vacuolar protein sorting-associated protein 13D; Functions in promoting mitochondrial clearance by mitochondrial autophagy (mitophagy), also possibly by positively regulating mitochondrial fission. Mitophagy plays an important role in regulating cell health and mitochondrial size and homeostasis. | 0.814 |
| ATG2B | ZZEF1 | ENSP00000353010 | ENSP00000371051 | Autophagy-related protein 2 homolog B; Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion; Belongs to the ATG2 family. | Zinc finger ZZ-type and EF-hand domain containing 1. | 0.448 |
| KIAA2013 | VPS13D | ENSP00000365756 | ENSP00000478104 | Uncharacterized protein KIAA2013; KIAA2013. | Vacuolar protein sorting-associated protein 13D; Functions in promoting mitochondrial clearance by mitochondrial autophagy (mitophagy), also possibly by positively regulating mitochondrial fission. Mitophagy plays an important role in regulating cell health and mitochondrial size and homeostasis. | 0.488 |
| MIGA2 | PLIN5 | ENSP00000351138 | ENSP00000371272 | Mitoguardin 2; Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family. | Perilipin-5; Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hyd [...] | 0.448 |
| MIGA2 | VPS13A | ENSP00000351138 | ENSP00000353422 | Mitoguardin 2; Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family. | Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane. | 0.418 |
| MIGA2 | VPS13D | ENSP00000351138 | ENSP00000478104 | Mitoguardin 2; Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family. | Vacuolar protein sorting-associated protein 13D; Functions in promoting mitochondrial clearance by mitochondrial autophagy (mitophagy), also possibly by positively regulating mitochondrial fission. Mitophagy plays an important role in regulating cell health and mitochondrial size and homeostasis. | 0.483 |
| PLIN5 | MIGA2 | ENSP00000371272 | ENSP00000351138 | Perilipin-5; Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hyd [...] | Mitoguardin 2; Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family. | 0.448 |
| PLIN5 | VPS13D | ENSP00000371272 | ENSP00000478104 | Perilipin-5; Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hyd [...] | Vacuolar protein sorting-associated protein 13D; Functions in promoting mitochondrial clearance by mitochondrial autophagy (mitophagy), also possibly by positively regulating mitochondrial fission. Mitophagy plays an important role in regulating cell health and mitochondrial size and homeostasis. | 0.521 |
| RHOT1 | VPS13D | ENSP00000351132 | ENSP00000478104 | Mitochondrial Rho GTPase 1; Mitochondrial GTPase involved in mitochondrial trafficking. Probably involved in control of anterograde transport of mitochondria and their subcellular distribution. | Vacuolar protein sorting-associated protein 13D; Functions in promoting mitochondrial clearance by mitochondrial autophagy (mitophagy), also possibly by positively regulating mitochondrial fission. Mitophagy plays an important role in regulating cell health and mitochondrial size and homeostasis. | 0.628 |
| TSG101 | VPS13D | ENSP00000251968 | ENSP00000478104 | Tumor susceptibility gene 101 protein; Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Mediates the association between the ESCRT-0 and ESCRT-I complex. Required for completion of cytokinesis; the function requires CEP55. May be involved in cell growth and differentiation. Acts as a negative growth regulator. Involved in the budding of many viruses through an interaction with viral proteins that contain a late-budding [...] | Vacuolar protein sorting-associated protein 13D; Functions in promoting mitochondrial clearance by mitochondrial autophagy (mitophagy), also possibly by positively regulating mitochondrial fission. Mitophagy plays an important role in regulating cell health and mitochondrial size and homeostasis. | 0.451 |
| VPS13A | ATG2B | ENSP00000353422 | ENSP00000353010 | Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane. | Autophagy-related protein 2 homolog B; Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion; Belongs to the ATG2 family. | 0.527 |
| VPS13A | MIGA2 | ENSP00000353422 | ENSP00000351138 | Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane. | Mitoguardin 2; Regulator of mitochondrial fusion: acts by forming homo- and heterodimers at the mitochondrial outer membrane and facilitating the formation of PLD6/MitoPLD dimers. May act by regulating phospholipid metabolism via PLD6/MitoPLD; Belongs to the mitoguardin family. | 0.418 |
| VPS13A | VPS13B | ENSP00000353422 | ENSP00000351346 | Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane. | Vacuolar protein sorting-associated protein 13B; May be involved in protein sorting in post Golgi membrane traffic; Belongs to the VPS13 family. | 0.667 |
| VPS13A | VPS13D | ENSP00000353422 | ENSP00000478104 | Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane. | Vacuolar protein sorting-associated protein 13D; Functions in promoting mitochondrial clearance by mitochondrial autophagy (mitophagy), also possibly by positively regulating mitochondrial fission. Mitophagy plays an important role in regulating cell health and mitochondrial size and homeostasis. | 0.556 |
| VPS13B | VPS13A | ENSP00000351346 | ENSP00000353422 | Vacuolar protein sorting-associated protein 13B; May be involved in protein sorting in post Golgi membrane traffic; Belongs to the VPS13 family. | Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane. | 0.667 |
| VPS13B | VPS13C | ENSP00000351346 | ENSP00000493560 | Vacuolar protein sorting-associated protein 13B; May be involved in protein sorting in post Golgi membrane traffic; Belongs to the VPS13 family. | Vacuolar protein sorting-associated protein 13C; Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential. Involved in the regulation of PINK1/PRKN-mediated mitophagy in response to mitochondrial depolarization. | 0.629 |
| VPS13B | VPS13D | ENSP00000351346 | ENSP00000478104 | Vacuolar protein sorting-associated protein 13B; May be involved in protein sorting in post Golgi membrane traffic; Belongs to the VPS13 family. | Vacuolar protein sorting-associated protein 13D; Functions in promoting mitochondrial clearance by mitochondrial autophagy (mitophagy), also possibly by positively regulating mitochondrial fission. Mitophagy plays an important role in regulating cell health and mitochondrial size and homeostasis. | 0.573 |
| VPS13C | ATG2B | ENSP00000493560 | ENSP00000353010 | Vacuolar protein sorting-associated protein 13C; Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential. Involved in the regulation of PINK1/PRKN-mediated mitophagy in response to mitochondrial depolarization. | Autophagy-related protein 2 homolog B; Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion; Belongs to the ATG2 family. | 0.423 |
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